4430-77-7

Basic information

• Product Name: Pyrido[2,3-d]pyridazine-5,8-diol
• Synonyms: Pyrido[2,3-d]pyridazine-5,8-diol;Pyrido[2,3-d]pyridazine-5,8-dione, 6,7-dihydro-;6,7-Dihydropyrido[2,3-d]pyridazine-5,8-dione
• CAS NO: 4430-77-7
• Molecular Formula: C₇H₅N₃O₂
• Molecular Weight: 163.135
• Mol File: 4430-77-7.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 563.1 °C at 760 mmHg
• Flash Point: 294.4 °C
• Appearance: /
• Density: 1.424 g/cm³
• Vapor Pressure: 2.76E-13mmHg at 25°C
• Refractive Index: 1.593
• CAS DataBase Reference: Pyrido[2,3-d]pyridazine-5,8-diol(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrido[2,3-d]pyridazine-5,8-diol(4430-77-7)
• EPA Substance Registry System: Pyrido[2,3-d]pyridazine-5,8-diol(4430-77-7)

Safety Data

• Hazardous Substances Data: 4430-77-7(Hazardous Substances Data)

Usage

Uses

6,7-Dihydro-pyrido[2,3-d]pyridazine-5,8-dione

InChI:InChI=1/C7H5N3O2/c11-6-4-2-1-3-8-5(4)7(12)10-9-6/h1-3H,(H,9,11)(H,10,12)

Upstream product

• 699-98-9 Pyridine-2,3-dicarboxylic anhydride 
• 89-00-9 Pyridine-2,3-dicarboxylic acid 
• 605-38-9 dimethyl 2,3-pyridinedicarboxylate 
• 76240-65-8 C₂₁H₁₃N₃O₂ 
• 91533-15-2 pyrido<2,3-d>pyridazine-5,8-dione 
• 23439-87-4 6-hydroxy-5H-pyrrolo[3,4-b]pyridine-5,7-(6H)-dione 
• 55155-23-2 2,3-pyridinedicarboxylic acid chloride 

Downstream Products

• 2398-81-4 Nicotinic acid N-oxide 
• 89663-08-1 pyrido<2,3-d>pyridazine-5,8-dione 1-oxide 
• 703-33-3 5,8-Dichloropyrido<2,3-d>pyridazine 
• 2942-32-7 6-Chloro-1,2,4-triazolo<4,3-b>pyrido<2,3-d>pyridazine 
• 2843-74-5 (5-chloro-pyrido[2,3-d]pyridazin-8-yl)-phenyl-amine 
• 2843-76-7 (4-chloro-phenyl)-(5-chloro-pyrido[2,3-d]pyridazin-8-yl)-amine 
• 2843-78-9 (4-bromo-phenyl)-(5-chloro-pyrido[2,3-d]pyridazin-8-yl)-amine 

Relevant articles and documents

2-D lanthanide-organic complexes constructed from 6,7-dihydropyrido(2,3-d) pyridazine-5,8-dione: Synthesis, characterization and photoluminescence for sensing small molecules

Four isostructural lanthanide-organic complexes [Ln(HPDH)(ox)(H 2O)]n (Ln = Eu3+1, Tb3+2, Sm 3+3, Gd3+4; H2PDH = 6,7-dihydropyrido(2,3-d) pyridazine-5,8-dione; H2ox = oxalic acid) have been synthesized successfully under hydrothermal conditions and characterized by means of elemental analysis, powder XRD, TG-DTA, IR and UV-vis spectroscopy. Complexes 1 and 2 were structurally characterized by single crystal X-ray diffraction analysis. All complexes are composed of 2-D layers, which further construct a 3-D supramolecular network. Each 2-D layer in complexes 1-4 is composed of 1-D Eu-ox infinite chains, which are further connected by biconnected HPDH - ligands. The photoluminescent properties of complexes 1-4 were studied in the solid state at room temperature. The singlet energy level (34722 cm-1) and the lowest triplet energy level (21786 cm-1) for the ligand H2PDH were calculated on the basis of its UV-vis absorbance edges (1 × 10-4 M in ethanol) and phosphorescence spectrum of complex 4 at 77 K, respectively. The complexes 1, 2, and 3 exhibit metal centered luminescence with characteristic red, green and pink emission, respectively. The energy transfer mechanism and photoluminescence properties were investigated. Complex 1, in which the energy transition from the triplet energy level (3ππ*) of ligand HPDH- to Eu3+ cation is more effective, has been selected as a representative to examine the potential for sensing small molecules by its luminescence properties in different emulsions. EtOH was found to be an excellent enhancing while DMF a highly quenching solvent in this study.

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Aim to find new compounds with stronger anticonvulsant activity and lower neurotoxicity, a novel series of 6-substituted-pyrido[3,2-d]pyridazine derivatives was synthesized using furo[3,4-b]pyridine-5,7-dione as the starting material. We evaluated their a