444682-16-0Relevant articles and documents
Synthesis and biological assessment of simplified analogues of the potent microtubule stabilizer (+)-discodermolide
Minguez, Jose M.,Kim, Sun-Young,Giuliano, Kenneth A.,Balachandran, Raghavan,Madiraju, Charitha,Day, Billy W.,Curran, Dennis P.
, p. 3335 - 3357 (2007/10/03)
An efficient, convergent and stereocontrolled synthesis of simplified analogues of the potent antimitotic agent (+)-discodermolide has been achieved and several small libraries have been prepared. In all the libraries, the discodermolide methyl groups at