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54911-85-2

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54911-85-2 Usage

Chemical Properties

Brown Liquid

Uses

4-Tetrahydropyranyloxy-butanal is a useful building block.

Check Digit Verification of cas no

The CAS Registry Mumber 54911-85-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,9,1 and 1 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 54911-85:
(7*5)+(6*4)+(5*9)+(4*1)+(3*1)+(2*8)+(1*5)=132
132 % 10 = 2
So 54911-85-2 is a valid CAS Registry Number.

54911-85-2Relevant articles and documents

Double cationic propargylation: From linear to polycyclic ethers

Diaz, David,Martin, Tomas,Martin, Victor S.

, p. 3289 - 3291 (2001)

Equation presented The trapping of cations generated from Co2(CO)6-bispropargylic alcohols provided diethers in good yield. The procedure is also valid when two vicinal acetylenes are present. The methodology can be applied to the sy

A scalable synthesis of (+)-coronafacic acid

Kato, Nobuki,Miyagawa, Saki,Nomoto, Haruna,Nakayama, Misuzu,Iwashita, Makoto,Ueda, Minoru

, p. 423 - 430 (2020)

A facile, efficient, and scalable synthesis of optically pure coronafacic acid by resolution of racemic coronafacic acid obtained using an improved version of Watson's method has been developed. By optimizing the boron-mediated aldol reaction of Watson, we were able to prepare 2.1 g of racemic coronafacic acid. This was coupled with (S)-4-isopropyl-2-oxazolidinone to give a mixture of diastereomeric coronafacyl oxazolidinones, which were readily separable by silica-gel column chromatography to give 630 mg of optically pure (+)-coronafacic acid.

4-Methyltetrahydropyran (4-MeTHP): Application as an Organic Reaction Solvent

Kobayashi, Shoji,Tamura, Tomoki,Yoshimoto, Saki,Kawakami, Takashi,Masuyama, Araki

, p. 3921 - 3937 (2019/11/11)

4-Methyltetrahydropyran (4-MeTHP) is a hydrophobic cyclic ether with potential for industrial applications. We herein report, for the first time, a comprehensive study on the performance of 4-MeTHP as an organic reaction solvent. Its broad application to organic reactions includes radical, Grignard, Wittig, organometallic, halogen-metal exchange, reduction, oxidation, epoxidation, amidation, esterification, metathesis, and other miscellaneous organic reactions. This breadth suggests 4-MeTHP can serve as a substitute for conventional ethers and harmful halogenated solvents. However, 4-MeTHP was found incompatible with strong Lewis acids, and the C?O bond was readily cleaved by treatment with BBr3. Moreover, the radical-based degradation pathways of 4-MeTHP, THP and 2-MeTHF were elucidated on the basis of GC-MS analyses. The data reported herein is anticipated to be useful for a broad range of synthetic chemists, especially industrial process chemists, when selecting the reaction solvent with green chemistry perspectives.

Au-catalyzed intramolecular hydroalkoxylation of gem-difluorinated alkynols

Hamel, Jean-Denys,Paquin, Jean-Fran?ois

, p. 11 - 23 (2018/10/20)

The intramolecular hydroalkoxylation of gem-difluorinated alkynols was found possible under Au catalysis, allowing for the preparation of a series of fluorinated heterocycles. The nature of the solvent was found to be especially critical in the cyclizatio

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