462-18-0 Usage
Description
7-Tridecanone is an organic compound that is an isomer of 2-Tridecanone, which is a flavor component found in many food products. However, 7-Tridecanone is much less distributed in comparison. It is a colorless liquid with a strong, fruity odor and is used for various applications, including studying the toxicity of narcotic industrial chemicals.
Uses
Used in Flavor Industry:
7-Tridecanone is used as a flavoring agent in the food industry due to its strong, fruity odor. It contributes to the enhancement of the taste and aroma of various food products.
Used in Chemical Research:
7-Tridecanone is used in chemical research to study the toxicity of narcotic industrial chemicals. Its properties and behavior can provide valuable insights into the effects of similar compounds on human health and the environment.
Used in Perfumery:
7-Tridecanone can also be used in the perfumery industry as a fragrance ingredient. Its strong, fruity scent can be incorporated into various perfumes and fragrances to create unique and appealing scents.
Synthesis Reference(s)
Journal of the American Chemical Society, 97, p. 6900, 1975 DOI: 10.1021/ja00856a069Tetrahedron Letters, 36, p. 3223, 1995 DOI: 10.1016/0040-4039(95)00519-I
Safety Profile
Moderately toxic by intravenousroute. A flammable liquid. When heated to decompositionit emits acrid smoke and irritating vapors.
Purification Methods
Crystallise the ketone from EtOH. [Beilstein 1 H 715.]
Check Digit Verification of cas no
The CAS Registry Mumber 462-18-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,6 and 2 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 462-18:
(5*4)+(4*6)+(3*2)+(2*1)+(1*8)=60
60 % 10 = 0
So 462-18-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H26O/c1-3-5-7-9-11-13(14)12-10-8-6-4-2/h3-12H2,1-2H3
462-18-0Relevant articles and documents
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Asinger,F. et al.
, p. 425 - 435 (1979)
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Highly productive α-alkylation of ketones with alcohols mediated by an Ir-oxalamidato/solid base catalyst system
Maeda, Hironori,Nara, Hideki,Shimizu, Hideo
supporting information, p. 2772 - 2779 (2020/12/29)
An Ir-oxalamidato complex in combination with a solid base (e.g., magnesium aluminometasilicate/Ca(OH)2) significantly improved the catalyst productivity in α-alkylation of methyl ketones with primary alcohols. Optimization through systematic variation of the oxalamidato ligand led to a practical turnover number (TON) of 10 000.40 000.
Dehydrogenative Coupling of Benzylic and Aldehydic C-H Bonds
Ishida, Naoki,Kawasaki, Tairin,Murakami, Masahiro
supporting information, p. 3366 - 3370 (2020/03/06)
A photoinduced dehydrogenative coupling reaction between benzylic and aldehydic C-H bonds is reported. When a solution of an alkylbenzene and an aldehyde in ethyl acetate is irradiated with visible light in the presence of iridium and nickel catalysts, a coupled α-aryl ketone is formed with evolution of dihydrogen. An analogous C-C bond forming reaction occurs between a C-H bond next to the nitrogen of an N-methylamide and an aldehydic C-H bond to produce an α-amino ketone. These reactions provide a straightforward pathway from readily available materials leading to valued structural motifs of pharmacological relevance.
