468740-86-5

Basic information

• Product Name: 2-(3-chloro-phenyl)-2-triethylsilanyloxy-ethylamine
• Synonyms: 2-(3-chloro-phenyl)-2-triethylsilanyloxy-ethylamine
• CAS NO: 468740-86-5
• Molecular Weight: 285.889
• Mol File: 468740-86-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(3-chloro-phenyl)-2-triethylsilanyloxy-ethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-chloro-phenyl)-2-triethylsilanyloxy-ethylamine(468740-86-5)
• EPA Substance Registry System: 2-(3-chloro-phenyl)-2-triethylsilanyloxy-ethylamine(468740-86-5)

Safety Data

• Hazardous Substances Data: 468740-86-5(Hazardous Substances Data)

Upstream product

• 587-04-2 m-Chlorobenzaldehyde 
• 39220-98-9 1-(3-chlorophenyl)-2-nitroethanol 
• 468740-85-4 [1-(3-Chloro-phenyl)-2-nitro-ethoxy]-triethyl-silane 

Downstream Products

• 53360-89-7 2-amino-1-(3-chloro-phenyl)-ethanol 
• 726206-27-5 4-[2-(3-chloro-phenyl)-2-hydroxy-ethylamino]-3-(1H-imidazo[4,5-c]pyridin-2-yl)-1H-pyridin-2-one 

Relevant articles and documents

Novel 1H-(benzimidazol-2-yl)-1H-pyridin-2-one inhibitors of insulin-like growth factor I (IGF-1R) kinase

A novel class of 1H-(benzimidazol-2-yl)-1H-pyridin-2-one inhibitors of insulin-like growth factor I (IGF-1R) kinase is described. This report discusses the SAR of 4-(2-hydroxy-2-phenylethylamino)-substituted pyridones with improved IGF-1R potency.

NOVEL TYROSINE KINASE INHIBITORS

The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof. The formula (I) compounds inhibit tyrosine kinase enzymes thereby making them useful as anti-cancer agents.