53360-89-7

Basic information

• Product Name: 2-AMINO-1-(3-CHLOROPHENYL)-1-ETHANOL
• Synonyms: 2-AMINO-1-(3-CHLOROPHENYL)-1-ETHANOL;(1R)-2-amino -1-(3-chlorophenyl) ethanol;(R)-(-)-2-AMINO-1-(4-CHLOROPHENYL)ETHANOL;BENZENEMETHANOL, α-(AMINOMETHYL)-3-CHLORO-
• CAS NO: 53360-89-7
• Molecular Formula: C₈H₁₀ClNO
• Molecular Weight: 171.62
• Mol File: 53360-89-7.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 319.8 °C at 760 mmHg
• Flash Point: 147.2 °C
• Appearance: /
• Density: 1.26 g/cm³
• Vapor Pressure: 0.000138mmHg at 25°C
• Refractive Index: 1.587
• PKA: 11.77±0.35(Predicted)
• CAS DataBase Reference: 2-AMINO-1-(3-CHLOROPHENYL)-1-ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-1-(3-CHLOROPHENYL)-1-ETHANOL(53360-89-7)
• EPA Substance Registry System: 2-AMINO-1-(3-CHLOROPHENYL)-1-ETHANOL(53360-89-7)

Safety Data

• Hazardous Substances Data: 53360-89-7(Hazardous Substances Data)

Usage

General Description

2-Amino-1-(3-chlorophenyl)-1-ethanol, also known as Chlorphenesin, is a chemical compound used as a muscle relaxant and a preservative in cosmetics and personal care products. It is derived from phenol and is commonly used in topical formulations to help alleviate muscle stiffness and tension. Chlorphenesin works by blocking nerve signals in the muscles, leading to a temporary decrease in muscle contractions and relaxation. It is considered safe for use in cosmetics when used in low concentrations, but prolonged or excessive exposure may cause skin irritation and allergic reactions in sensitive individuals. Therefore, it is important to follow recommended guidelines for product usage and to consult with a healthcare professional if any adverse reactions occur.

InChI:InChI=1/C8H10ClNO/c9-7-3-1-2-6(4-7)8(11)5-10/h1-4,8,11H,5,10H2

Upstream product

• 97070-75-2 2-(3-chlorophenyl)-2-hydroxyacetonitrile 
• 7677-24-9 trimethylsilyl cyanide 
• 587-04-2 m-Chlorobenzaldehyde 
• 468740-86-5 2-(3-chloro-phenyl)-2-triethylsilanyloxy-ethylamine 
• 39220-98-9 1-(3-chlorophenyl)-2-nitroethanol 
• 454-89-7 3-Trifluoromethylbenzaldehyde 
• 157028-15-4 4-(methoxymethoxy)-3,5-dimethylbenzaldehyde 

Downstream Products

• 101812-74-2 5-(3-chloro-phenyl)-4,5-dihydro-oxazol-2-ylamine 
• 173373-97-2 5-(3-chlorophenyl)oxazolidine 
• 468734-63-6 (+/-)-2-{4-[2-(3-chloro-phenyl)-2-hydroxy-ethylamino]-2-oxo-1,2-dihydro-pyridin-3-yl}-7-methyl-3H-benzimidazole-5-carbonitrile 
• 153292-24-1 5-(4-{2-[2-(3-chlorophenyl)-2-hydroxyethylamino]propoxy}benzyl)thiazolidine-2,4-dione 
• 153291-86-2 2-[2-(4-methoxycarbonylmethyl-2-chlorophenoxy)-1-methylethyl]amino-1-(3-chlorophenyl)ethanol 

Relevant articles and documents

1,6- AND 1,8-NAPHTHYRIDINES

Compounds of formula and pharmaceutically acceptable salts thereof are described, as well as the pharmaceutical compositions containing said compounds and their pharmaceutically acceptable salts, and the use of said compounds and pharmaceutical compositions for the treatment, control or amelioration of proliferative diseases, including cancer, Down syndrome or early onset Alzheimer's disease.

PYRAZOLO PYRIMIDINES AS DYRK1A AND DYRK1B INHIBITORS

Compounds of formula and pharmaceutically acceptable salts thereof are described, as well as the pharmaceutical compositions containing said compounds and their pharmaceutically acceptable salts, and the use of said compounds and pharmaceutical compositions for the treatment, control or amelioration of proliferative diseases, including cancer, Down syndrome or early onset Alzheimer's disease.

PYRAZOLO PYRIMIDINES

Compounds of formula and pharmaceutically acceptable salts thereof are described, as well as the pharmaceutical compositions containing said compounds and their pharmaceutically acceptable salts, and the use of said compounds and pharmaceutical compositions for the treatment, control or amelioration of proliferative diseases, including cancer, Down syndrome or early onset Alzheimer's disease.