477293-60-0

Basic information

• Product Name: (2S, 4S)-4-Hydroxy-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester
• Synonyms: (2S, 4S)-4-Hydroxy-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester;(2S,4S)-tert-Butyl 4-hydroxy-2-methylpyrrolidine-1-carboxylate;1-Pyrrolidinecarboxylic acid, 4-hydroxy-2-methyl-, 1,1-dimethylethyl ester, (2S,4S)-;tert-butyl (2S,4S)-4-hydroxy-2-methylpyrrolidine-1-carboxylate;(2S,4S)-4-HYDROXY-2-METHYL-1-PYRROLIDINECARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER;1,1-dimethylethyl (2S,4S)-4-hydroxy-2-methyl-1-pyrrolidinecarboxylate
• CAS NO: 477293-60-0
• Molecular Formula: C₁₀H₁₉NO₃
• Molecular Weight: 201.26276
• Mol File: 477293-60-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 282.5±33.0 °C(Predicted)
• Appearance: /
• Density: 1.094±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.75±0.40(Predicted)
• CAS DataBase Reference: (2S, 4S)-4-Hydroxy-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S, 4S)-4-Hydroxy-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester(477293-60-0)
• EPA Substance Registry System: (2S, 4S)-4-Hydroxy-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester(477293-60-0)

Safety Data

• Hazardous Substances Data: 477293-60-0(Hazardous Substances Data)

Usage

General Description

"(2S, 4S)-4-Hydroxy-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester" is a chemical compound that is a derivative of the naturally occurring amino acid proline. It is a tert-butyl ester, which means that it is a derivative of proline with a tert-butyl group attached to the carboxyl group. (2S, 4S)-4-Hydroxy-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester has potential applications in the pharmaceutical industry, particularly as a building block for the synthesis of certain drugs or as a chiral auxiliary in asymmetric synthesis. It may also have uses in the development of new materials or as a chemical intermediate in organic synthesis.

Upstream product

• 477293-59-7 (2S,4S)-4-Formyloxy-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 114676-61-8 tert-butyl (2S,4R)-4-hydroxyl-2-methylpyrrolidine-1-carboxylate 
• 1123305-80-5 1,1-dimethylethyl (2S,4S)-4-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-2-methyl-1-pyrrolidinecarboxylate 
• 791602-89-6 4-(tert-butyldimethylsilanyloxy)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 924907-62-0 1,1-dimethylethyl (2R,4S)-4-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-2-{[(methylsulfonyl)oxy]methyl}-1-pyrrolidinecarboxylate 
• 135042-17-0 (2R,4S)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 
• 178962-09-9 methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate 
• 3398-22-9 trans-4-hydroxyproline 
• 134441-72-8 1,1-dimethylethyl (2R,4S)-4-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-2-(hydroxymethyl)-1-pyrrolidinecarboxylate 

Downstream Products

• 477293-64-4 C₃₅H₄₇NO₃S 
• 1123307-53-8 2,5-dibromo-N-[(3R,5S)-1-cyano-5-methyl-3-pyrrolidinyl]benzenesulfonamide 
• 1123305-82-7 1,1-dimethylethyl (2S,4R)-4-{[(2,5-dibromophenyl)sulfonyl]amino}-2-methyl-1-pyrrolidinecarboxylate 
• 708274-46-8 1,1-dimethylethyl (2S,4R)-4-amino-2-methyl-1-pyrrolidinecarboxylate 
• 1123309-12-5 C₁₁H₁₄Br₂N₂O₂S 

Relevant articles and documents

HETEROCYCLE DERIVATIVE HAVING PGD2 RECEPTOR ANTAGONIST ACTIVITY

The present invention is related to a compound represented by formula (I), wherein X1, X2, X3, X4, X5, R5, R6, R7, R8, n, p, q, ring A and ring B are as described in the specification, or a

NOVEL CATHEPSIN C INHIBITORS AND THEIR USE

The invention is directed to compounds according to Formula (I) wherein R1, R2a, R2b, R2c, R3, and n are defined below, and to pharmaceutically-acceptable salts thereof. They are cathepsin C inhibitors and can be used in the treatment of diseases mediated