477293-64-4Relevant articles and documents
Synthesis and evaluation of novel pyrrolidinyl sordaricin derivatives as antifungal agents
Arai, Masami,Harasaki, Tamako,Fukuoka, Takashi,Kaneko, Satoru,Konosu, Toshiyuki
, p. 2733 - 2736 (2007/10/03)
N-Benzyl pyrrolidinyl sordaricin derivatives have been synthesized from cis-4-hydroxy-D-proline in a stereocontrolled manner. These compounds maintained moderate antifungal activity against several pathogenic fungal strains. Their MIC values against Candida albicans were in the range of 0.25-2 μg/mL.