4954-14-7 Usage
Description
1,3,5(10)-ESTRATRIEN-17-ALPHA-METHYL-3,17-BETA-DIOL 3-METHYL ETHER, also known as 17β-Estradiol derivative, is a hormone secreted by premenopausal ovaries. It is an off-white solid with unique chemical properties that make it suitable for various applications across different industries.
Uses
Used in Pharmaceutical Industry:
1,3,5(10)-ESTRATRIEN-17-ALPHA-METHYL-3,17-BETA-DIOL 3-METHYL ETHER is used as a hormone replacement therapy agent for managing symptoms of menopause, such as hot flashes, night sweats, and vaginal dryness. Its application in this industry is due to its ability to mimic the effects of the naturally occurring hormone, 17β-Estradiol.
Used in Cosmetics Industry:
In the cosmetics industry, 1,3,5(10)-ESTRATRIEN-17-ALPHA-METHYL-3,17-BETA-DIOL 3-METHYL ETHER is used as an ingredient in anti-aging products for its potential estrogenic effects on the skin. It is believed to help improve skin elasticity, reduce wrinkles, and maintain skin hydration.
Used in Research and Development:
1,3,5(10)-ESTRATRIEN-17-ALPHA-METHYL-3,17-BETA-DIOL 3-METHYL ETHER is used as a research compound for studying the effects of estrogen on various biological processes. Its application in this field is due to its structural similarity to the naturally occurring hormone, allowing scientists to investigate its potential therapeutic and pharmacological properties.
Used in Veterinary Medicine:
In veterinary medicine, 1,3,5(10)-ESTRATRIEN-17-ALPHA-METHYL-3,17-BETA-DIOL 3-METHYL ETHER is used as a hormone supplement to treat reproductive issues in animals, such as irregular estrous cycles or infertility. Its application in this industry is based on its ability to regulate hormonal balance and support normal reproductive function.
Check Digit Verification of cas no
The CAS Registry Mumber 4954-14-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,9,5 and 4 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4954-14:
(6*4)+(5*9)+(4*5)+(3*4)+(2*1)+(1*4)=107
107 % 10 = 7
So 4954-14-7 is a valid CAS Registry Number.
4954-14-7Relevant articles and documents
Rhodium-Catalyzed β-Dehydroborylation of Silyl Enol Ethers: Access to Highly Functionalized Enolates
Li, Jie,Li, Ruoling,Yang, Wen,Zhao, Pei,Zhao, Wanxiang
supporting information, p. 9580 - 9585 (2021/12/14)
An efficient rhodium-catalyzed β-dehydroborylation of aldehyde-derived silyl enol ethers (SEEs) with bis(pinacolato)diboron (B2pin2) is disclosed. The borylation reactions proceeded well with alkyl- and aryl-substituted SEEs, affording a wide array of valuable functionalized β-boryl silyl enolates with high efficiency and excellent stereoselectivity. Moreover, the borylated products, through versatile carbon–boron bond transformations, were readily converted into diverse synthetically useful molecules, including α-hydroxy ketones, functionalized SEEs, and gem-difunctionalized aldehydes.
Nickel-catalyzed alkynylation of anisoles via C-O bond cleavage
Tobisu, Mamoru,Takahira, Tsuyoshi,Ohtsuki, Akimichi,Chatani, Naoto
supporting information, p. 680 - 683 (2015/03/05)
A new cross-coupling reaction has been developed for the introduction of an alkyne moiety to an anisole derivative through C-O bond activation using an NHC ligand. This method has been used for direct alkynylation of a broad range of anisole derivatives a
Improved arene fluorination methodology for I(III) salts
Wang, Bijia,Qin, Linlin,Neumann, Kiel D.,Uppaluri, Shriharsha,Cerny, Ronald L.,DiMagno, Stephen G.
supporting information; experimental part, p. 3352 - 3355 (2010/11/02)
(Equation Presented). The use of low polarity aromatic solvents (benzene or toluene) and/or the removal of inorganic salts results in dramatically improved yields of fluorinated arenes from diaryliodonium salts. This methodology is shown to "scale down" to the conditions used typically for radiotracer synthesis.
