50800-82-3

Basic information

• Product Name: 1H-Pyrazole, 3,5-bis(4-chlorophenyl)-4,5-dihydro-
• CAS NO: 50800-82-3
• Molecular Formula: C15H12Cl2N2
• Molecular Weight: 291.18
• Mol File: 50800-82-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazole, 3,5-bis(4-chlorophenyl)-4,5-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole, 3,5-bis(4-chlorophenyl)-4,5-dihydro-(50800-82-3)
• EPA Substance Registry System: 1H-Pyrazole, 3,5-bis(4-chlorophenyl)-4,5-dihydro-(50800-82-3)

Safety Data

• Hazardous Substances Data: 50800-82-3(Hazardous Substances Data)

Usage

Derivative of pyrazole

yes

Also known as

Cl-4-phenylpyrazole

Potential applications

medicinal chemistry

Investigated as

antitumor agent, selective inhibitor of aromatase enzyme

Role

modulation of various biological processes

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 99-91-2 para-chloroacetophenone 
• 20725-25-1 1,3-bis(4-chlorophenyl)prop-2-en-1-one 
• 19672-59-4 (E)-1,3-di(4-chlorophenyl)-2-propen-1-one 

Downstream Products

• 1381883-56-2 (3,5-bis(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)(6-methylpyridin-3-yl)methanone 
• 1381883-52-8 (3,5-bis(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)(5-bromopyridin-3-yl)methanone 
• 1381883-53-9 (3,5-bis(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)(6-chloropyridin-3-yl)methanone 
• 1381883-55-1 (3,5-bis(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)(2-chloropyridin-3-yl)methanone 
• 1381883-54-0 (3,5-bis(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)(2-chloro-6-methylpyridin-3-yl)methanone 
• 1235721-92-2 [3-(4-chlorophenyl)-5-(4-chlorophenyl)-4,5-dihydropyrazol-1-yl](pyridine-4-yl)methanone 
• 37865-30-8 3,5-bis-(4-chloro-phenyl)-4,5-dihydro-pyrazole-1-carbothioic acid anilide 

Relevant articles and documents

N1-benzenesulfonyl-2-pyrazoline hybrids in neurological disorders: Syntheses, biological screening and computational studies

A novel series of 1,3,5-trisubstituted-2-pyrazolines (5a-5t) was prepared via Claisen Schmidt condensation, followed by heterocyclization with hydrazine hydrate, substitution of N1 hydrogen of 2-pyrazoline nucleus with 4-chlorobenzenesulfonylchloride, app

An expeditious one-pot microwave facilitated versus conventional syntheses: In vivo biological screening and molecular docking studies of some 3,5-disubstituted-4,5-dihydro-(1H)-pyrazole derivatives

A series of 3,5-disubstituted-2-pyrazoline derivatives (2a-2t) were synthesized by reacting different aromatic/heteroaromatic aldehydes and ketones, in a two-step reaction through Claisen Schmidt condensation, followed by cyclization of the resulted chalc

SOCl2 catalyzed cyclization of chalcones: Synthesis and spectral studies of some bio-potent 1H pyrazoles

Some aryl-aryl 1H pyrazoles have been synthesised by cyclization of aryl chalcones and hydrazine hydrate in the presence of SOCl2. The yields of the pyrazoles are more than 85%. These pyrazoles are characterized by their physical con