50920-64-4

Basic information

• Product Name: 4-BROMO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER
• Synonyms: Ethyl 1-ethyl-3-methylpyrazole-5-carboxylate;Ethyl 2-ethyl-5-methylpyrazole-3-carboxylate
• CAS NO: 50920-64-4
• Molecular Formula: C₉H₁₄N₂O₂
• Molecular Weight: 182.22
• Mol File: 50920-64-4.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-BROMO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER(50920-64-4)
• EPA Substance Registry System: 4-BROMO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER(50920-64-4)

Safety Data

• Hazardous Substances Data: 50920-64-4(Hazardous Substances Data)

Usage

General Description

4-Bromo-1,3-dimethyl-1H-pyrazole-5-carboxylic acid ethyl ester is a chemical compound with the molecular formula C9H12BrN3O2. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 4-BROMO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER is known for its inhibitory effects on certain enzymes and has been studied for its potential therapeutic applications in cancer and other diseases. It is a white to off-white solid that is soluble in organic solvents and is typically handled and stored under controlled conditions to prevent degradation or contamination. The ethyl ester form of this compound allows for enhanced stability and bioavailability in various applications.

Upstream product

• 74-96-4 ethyl bromide 
• 4027-57-0 ethyl 5-methyl-2H-pyrazole-3-carboxylate 
• 64-67-5 diethyl sulfate 
• 615-79-2 ethyl 2,4-diketopentanoate 
• 624-80-6 ethylhydrazine 
• 50920-65-5 1-ethyl-3-methyl-1H-pyrazole-5-carboxylic acid 
• 64-17-5 ethanol 
• 95-92-1 oxalic acid diethyl ester 
• 67-64-1 acetone 
• 75-00-3 chloroethane 

Downstream Products

• 94192-28-6 N-[4-(2-Ethyl-5-methyl-2H-pyrazole-3-carbonyl)-2,5-dimethyl-2H-pyrazol-3-yl]-benzamide 
• 50920-65-5 1-ethyl-3-methyl-1H-pyrazole-5-carboxylic acid 
• 1253428-85-1 3-(1-ethyl-3-methylpyrazol-5-yl)-2-(4-tertbutylphenyl)-3-hydroxy-acrylonitrile 
• 1253431-45-6 3-(4-chloro-1-ethyl-3-methylpyrazol-5-yl)-2-(4-tertbutylphenyl)-3-hydroxy-acrylonitrile 
• 1253430-02-2 3-(1-ethyl-3,4-dimethylpyrazol-5-yl)-2-(4-tertbutylphenyl)-3-hydroxyl-acrylonitrile 

Relevant articles and documents

A method for preparing acetazole nitrile intermediate

The present invention relates to chemical synthesis, in particular a method for preparing a thyazole mite nitrile intermediate (3-methyl-1-ethyl-1H- ethylazole-5-carboxylate) method. The pyrazole ester under solvent conditions, added an acid binding agent and catalyst, into the system into the halogenated ethane gas, the reaction to qualified, to obtain ethyl. The present invention uses haloethane instead of diethyl sulfate for ethylation reaction, the reaction raw material is cheap and easy to obtain, and the process of post-treatment with water is cancelled, the COD emission is reduced directly from the process source, and the reaction cycle is greatly reduced.

STING AGONISTS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the modulation of STING, and the treatment of STING-mediated disorders.

Method for preparing 1-alkyl-3-alkylpyrazole-5-carboxylate

The invention discloses a preparation method of a compound shown in a formula (I). The compound is prepared through three-step reactions comprising condensation, condensation cyclization and alkylation, The preparation method provided by the invention can realize one-pot operation, a reactor is not required to be replaced, the yield of the prepared product is high, and the method is suitable for industrial production.