51224-09-0

Basic information

• Product Name: Acetamide, 2,2,2-trifluoro-N-[6-[[(4-methylphenyl)sulfonyl]oxy]hexyl]-
• CAS NO: 51224-09-0
• Molecular Formula: C15H20F3NO4S
• Molecular Weight: 367.389
• Mol File: 51224-09-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Acetamide, 2,2,2-trifluoro-N-[6-[[(4-methylphenyl)sulfonyl]oxy]hexyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2,2,2-trifluoro-N-[6-[[(4-methylphenyl)sulfonyl]oxy]hexyl]-(51224-09-0)
• EPA Substance Registry System: Acetamide, 2,2,2-trifluoro-N-[6-[[(4-methylphenyl)sulfonyl]oxy]hexyl]-(51224-09-0)

Safety Data

• Hazardous Substances Data: 51224-09-0(Hazardous Substances Data)

Upstream product

• 407-25-0 trifluoroacetic anhydride 
• 40248-34-8 6-trifluoroacetamido-1-hexanol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 912641-65-7 5'-O-(4,4'-dimethoxytrityl)-N⁶-(2-phenoxyacetyl)-2'-O-(6-trifluoroacetamido)hexyladenosine 
• 912641-74-8 5'-O-(4,4'-dimethoxytrityl)-2'-O-(6-trifluoroacetamido)hexyluridine 
• 912641-63-5 N⁶-(2-phenoxyacetyl)-2'-O-(6-trifluoroacetamido)hexyladenosine 
• 51224-10-3 1-iodo-6-(trifluoroacetamido)hexane 

Relevant articles and documents

Site-Selective Defluorinative sp3C-H Alkylation of Secondary Amides

A site-selective defluorinative sp3 C-H alkylation of secondary amides that rapidly and reliably incorporates gem-difluoroalkene motifs into previously unfunctionalized sp3 sites is disclosed. This protocol is distinguished by its mild conditions, wide scope, and exquisite site-selectivity, thus unlocking a new platform to introduce carbonyl isosteres at saturated hydrocarbon sites.