51336-03-9

Basic information

• Product Name: 4-Quinolinamine, 2-methyl-N-phenyl-
• CAS NO: 51336-03-9
• Molecular Formula: C16H14N2
• Molecular Weight: 234.301
• Mol File: 51336-03-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 4-Quinolinamine, 2-methyl-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Quinolinamine, 2-methyl-N-phenyl-(51336-03-9)
• EPA Substance Registry System: 4-Quinolinamine, 2-methyl-N-phenyl-(51336-03-9)

Safety Data

• Hazardous Substances Data: 51336-03-9(Hazardous Substances Data)

Upstream product

• 98-50-0 p-aminophenylarsonic acid 
• 103-84-4 Acetanilid 
• 10025-87-3 trichlorophosphate 
• 31835-53-7 4-methoxy-2-methyl-quinoline 
• 62-53-3 aniline 
• 5660-24-2 2-methyl-1H-quinolin-4-one 
• 4295-06-1 4-chloro-2-methylquinoline 
• 607-67-0 4-hydroxy-2-methylquinoline 

Downstream Products

• 4295-28-7 6-methyl-11H-indolo[3,2-c]-quinoline 

Relevant articles and documents

Microwave-assisted efficient synthesis of 4-substituted amino-2-methylquinolines catalyzed by p-toluenesulfonic acid

A series of novel 4-subtituted amino-2-methylquinolines (3a-3o) were readily synthesized via the reaction of 4-chloro-2-methylquinoline with amines catalyzed by p-toluenesulfonic acid (TsOH) at 120°C for 1 h under microwave-assisted organic synthesis (MAO

Synthesis method of aza-arylamine compound and aza-arylamine compound

The invention provides a synthesis method of an aza-arylamine compound as shown in a formula (I). The synthesis method comprises the following steps: an aza aromatic hydrocarbon compound as shown in aformula (II) reacts with an amine compound as shown in a formula (III) in presence of alkali and under a heating condition, so that u X substituent groups on an A ring of the compound as shown in theformula (II) are substituted by NRR in the compound as shown in the formula (III), and the compound as shown in the formula (I) is obtained, wherein A is an aza six-membered aromatic ring or five-membered aromatic ring, and is an independent single ring or is fused with a ring B; X refers to that the A ring has at least n X substituent groups, each X substituent group is independently selected from the group consisting of F, Cl, Br, I, CN, alkoxy of C and alkylthio of C, and n is a positive integer selected from 1-5; and the alkali is one or a mixture of more selected fromof BuOK, BuONa, BuONa, KHMDS, NaHMDS and LiHMDS. The synthesis method provided by the invention does not need the use of transition metal catalysts, is simple and convenient to operate, is economical and practical and is environmentally friendly. In addition, the invention also provides the aza-arylamine compound prepared by the method.

Synthesis of novel alkyl and aryl substituted dibenzo[b,h][1,6] naphthyridines

A one-pot synthesis of 7-alkyl and aryl substituted dibenzo[b,h][1,6] naphthyridines is reported from the reaction of 4-chloro-2-methylquinolines and alkyl/aryl substituted aminoketones. Because the yield of the dibenzonaphthyridines was poor, in an alter