51390-16-0

Basic information

• Product Name: 1-(4-methylphenyl)-3,5-diphenyl-1H-pyrazole
• Synonyms: 1-(4-methylphenyl)-3,5-diphenyl-1H-pyrazole
• CAS NO: 51390-16-0
• Molecular Weight: 310.398
• Mol File: 51390-16-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1-(4-methylphenyl)-3,5-diphenyl-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-methylphenyl)-3,5-diphenyl-1H-pyrazole(51390-16-0)
• EPA Substance Registry System: 1-(4-methylphenyl)-3,5-diphenyl-1H-pyrazole(51390-16-0)

Safety Data

• Hazardous Substances Data: 51390-16-0(Hazardous Substances Data)

Upstream product

• 637-60-5 p-tolylhydrazine hydrochloride 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 64747-58-6 N-((2E)-1,3-diphenylprop-2-en-1-ylidene)-4-methylaniline 
• 100-52-7 benzaldehyde 
• 539-44-6 N-4-methylphenylhydrazine 
• 70-11-1 α-bromoacetophenone 
• 1858-99-7 benzaldehyde p-tolylhydrazone 
• 2515-55-1 3,5-diphenyl-1-p-tolyl-4,5-dihydro-1H-pyrazole 
• 94-41-7 benzalacetophenone 
• 120-46-7 1,3-diphenylpropanedione 
• 98-86-2 acetophenone 
• 1145-01-3 3,5-Diphenylpyrazole 
• 120976-84-3 phenyl(p-tolyl)iodonium trifluoromethanesulfonate 
• 1120-90-7 3-iodopyridine 

Relevant articles and documents

TBHP/Cu(OAc)2 mediated oxidation of pyrazolines: A convenient method for the preparation of pyrazoles

An efficient and simple oxidative protocol has been developed for the preparation of pyrazoles from pyrazolines mediated by TBHP/Cu(OAc)2 at room temperature. The present protocol has been successfully applied for the preparation of various pyrazole compounds from heterocyclic pyrazolines.

Visible light mediated metal-free oxidative aromatization of 1,3,5-trisubstituted pyrazolines

The visible light mediated oxidation of 1,3,5-trisubstituted pyrazolines under metal-free conditions was developed. Various substituted pyrazolines were oxidized to pyrazoles by irradiation with visible light/sunlight. A plausible mechanism was proposed f

Radical Addition of Hydrazones by α-Bromo Ketones to Prepare 1,3,5-Trisubstituted Pyrazoles via Visible Light Catalysis

A novel efficient tandem reaction of hydrazones and α-bromo ketones is reported for the preparation of 1,3,5-trisubstituted pyrazoles by visible light catalysis. In this system, the monosubstituted hydrazones show wonderful reaction activity with alkyl radicals, generated from α-bromo ketones. A radical addition followed by intramolecular cyclization affords the important pyrazole skeleton in good to excellent yields. This efficient strategy under mild conditions with wide group tolerance provides a potential approach to the 1,3,5-trisubstituted pyrazoles.