51765-51-6 Usage
Description
(2-PHENOXY)METHYLSULFONYLANILINE, also known as 2''-Phenoxymethanesulfonanilide, is a metabolite of nimesulide (N477500), an anti-inflammatory agent. It is characterized by its ability to preferentially inhibit COX-2 over COX-1, which contributes to its anti-inflammatory properties. Additionally, it has been shown to suppress chemical-induced carcinogenesis in mice and rats and inhibit LPS-induced TNF-alpha production.
Uses
Used in Pharmaceutical Industry:
(2-PHENOXY)METHYLSULFONYLANILINE is used as an active pharmaceutical ingredient for its anti-inflammatory properties. It is particularly effective due to its preferential inhibition of COX-2 over COX-1, making it a potential candidate for the development of new anti-inflammatory drugs.
Used in Cancer Research:
In the field of cancer research, (2-PHENOXY)METHYLSULFONYLANILINE is used as a compound with potential anti-cancer properties. Its ability to suppress chemical-induced carcinogenesis in mice and rats makes it a valuable tool for studying the mechanisms of cancer development and progression.
Used in Immunology:
(2-PHENOXY)METHYLSULFONYLANILINE is used as a research compound in immunology, specifically for studying the regulation of LPS-induced TNF-alpha production. This application helps researchers understand the complex interactions between the immune system and inflammatory processes, potentially leading to the development of new therapeutic strategies for various immune-related disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 51765-51-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,7,6 and 5 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 51765-51:
(7*5)+(6*1)+(5*7)+(4*6)+(3*5)+(2*5)+(1*1)=126
126 % 10 = 6
So 51765-51-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H13NO3S/c1-18(15,16)14-12-9-5-6-10-13(12)17-11-7-3-2-4-8-11/h2-10,14H,1H3
