518021-24-4

Basic information

• Product Name: C₁₆H₁₉O₄
• CAS NO: 518021-24-4
• Molecular Weight: 275.324
• Mol File: 518021-24-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₆H₁₉O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₁₉O₄(518021-24-4)
• EPA Substance Registry System: C₁₆H₁₉O₄(518021-24-4)

Safety Data

• Hazardous Substances Data: 518021-24-4(Hazardous Substances Data)

Upstream product

• 108-59-8 malonic acid dimethyl ester 
• 100959-88-4 (2-iodo-3-methylphenyl)methanol 
• 99848-41-6 1-(bromomethyl)-2-iodo-3-methylbenzene 
• 108078-14-4 2-iodo-3-methylbenzoic acid 
• 4389-45-1 3-methylantranilic acid 
• 40637-56-7 dimethyl allylmalonate 
• 518021-15-3 2-allyl-2-(2-iodo-3-methylbenzyl)malonic acid dimethyl ester 

Relevant articles and documents

Quantitating the effect of an ortho substituent on cyclization and intramolecular hydrogen-transfer reactions of aryl radicals

Reduction of allyl 2-iodobenzyl malonates with triphenyltin hydrides generates aryl radicals that partition between 6-exo cyclization, 7-endo cyclization, and 1,5-hydrogen atom transfer. Rate constants for all of these processes are high (> 108 M-1 s-1), and the rates are only marginally reduced (33%) by the introduction of methyl group ortho to the reacting radical.