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5197-62-6

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5197-62-6 Usage

Description

2-[2-(2-Chloroethoxy)ethoxy]ethanol, also known as a chloro-ether derivative, is a colorless liquid with unique chemical properties. It is characterized by its chloroethoxyethoxyethanol structure, which grants it specific reactivity and solubility characteristics. This versatile compound is widely utilized in various chemical and pharmaceutical applications due to its functional groups and reactivity.

Uses

Used in Chemical Synthesis:
2-[2-(2-Chloroethoxy)ethoxy]ethanol is used as a synthetic intermediate for the preparation of ethylene glycol-based amino acids. Its chloroethoxyethoxyethanol structure allows for the formation of various amino acid derivatives, which are essential building blocks in the pharmaceutical and biotechnology industries.
Used in Polymer Synthesis:
In the field of molecular biology, 2-[2-(2-Chloroethoxy)ethoxy]ethanol is used as a key component in the preparation of polymers for direct and amplified DNA detection. These polymers play a crucial role in enhancing the sensitivity and accuracy of DNA detection methods, which are vital for research, diagnostics, and forensic applications.
Used in Pharmaceutical Synthesis:
2-[2-(2-Chloroethoxy)ethoxy]ethanol is also utilized in the synthesis of various pharmaceutical compounds, such as 1-[3-(2-aminoethyl)-1H-indol-5-yloxy]-3,6-dioxa-8-mercaptooctane. 2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL serves as a precursor for the development of new drugs with potential therapeutic applications.
Used in Oligonucleotide Synthesis:
In the field of molecular biology, 2-[2-(2-Chloroethoxy)ethoxy]ethanol is employed in the synthesis of modified oligonucleotides bearing a disulfide or a thiol function at the 3′-end and other modifications at the 5′-end. These modified oligonucleotides are essential for the development of novel gene therapies, antisense therapies, and other genetic engineering applications.
Used in the Chemical Industry:
2-[2-(2-Chloroethoxy)ethoxy]ethanol is used as a reagent in various chemical reactions, such as substitution, addition, and condensation reactions. Its unique structure and reactivity make it a valuable component in the synthesis of a wide range of chemical products, including pharmaceuticals, agrochemicals, and specialty chemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 5197-62-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,9 and 7 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5197-62:
(6*5)+(5*1)+(4*9)+(3*7)+(2*6)+(1*2)=106
106 % 10 = 6
So 5197-62-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H13ClO3/c7-1-3-9-5-6-10-4-2-8/h8H,1-6H2

5197-62-6Relevant articles and documents

Smooth receptor ligand

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Paragraph 0085; 0252; 0254; 0263, (2020/04/01)

The invention relates to the technical field of biology, particularly to a smooth receptor ligand, and provides a smooth receptor ligand or an isomer prodrug, a solvate and a pharmaceutically acceptable salt thereof, wherein the structural formula of the smooth receptor ligand is A-linker-B, A is an extracellular domain ligand structure, B is a transmembrane domain ligand structure, and Linker isa linear subunit inactive to the smooth receptor. According to the novel double-end small molecule ligand for the smooth receptor, by combining the crystal structure data of the smooth receptor, a linker is introduced into the proper sites of an extracellular domain ligand and a transmembrane domain ligand to obtain brand-new double-end ligand small molecules, so that the interaction between the ligand and the receptor and the biological activity of the ligand are enhanced.

A 2- chlorine ethoxy group -2-ethoxy-ethanol preparation method (by machine translation)

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Paragraph 0039; 0040, (2017/01/02)

The invention discloses a preparation method of 2-chloroethoxy-2-ethyoxylethanol. The preparation method comprises the steps: with 2-chloroethoxy and ethylene oxide as raw materials, performing a reaction in the presence of a catalyst to firstly obtain 2-ethyoxylethanol, removing the remaining solvent, namely a reactant 2-chlorohydrin, making the 2-ethyoxylethanol continuously react with the re-added ethylene oxide to obtain a target product 2-chloroethoxy-2-ethyoxylethanol. The preparation method has the advantages of being easy to operate during reaction, mild in system, less in side reactions, high in content and yield of products, and less in pollutants generated during the reaction.

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