5221-66-9

Basic information

• Product Name: 2,2-diphenyl-N-prop-2-ynyl-acetamide
• Synonyms: 2,2-diphenyl-N-prop-2-ynyl-acetamide
• CAS NO: 5221-66-9
• Molecular Weight: 249.312
• Mol File: 5221-66-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,2-diphenyl-N-prop-2-ynyl-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-diphenyl-N-prop-2-ynyl-acetamide(5221-66-9)
• EPA Substance Registry System: 2,2-diphenyl-N-prop-2-ynyl-acetamide(5221-66-9)

Safety Data

• Hazardous Substances Data: 5221-66-9(Hazardous Substances Data)

Upstream product

• 1871-76-7 diphenylacetic acid chloride 
• 2450-71-7 Propargylamine 
• 15430-52-1 prop-2-yn-1-amine hydrochloride 

Downstream Products

• 1273533-37-1 2-(2-benzhydryl-5-methyl-imidazol-1-yl)pyridine 
• 1273533-35-9 2-benzhydryl-5-methyl-1-phenyl-1H-imidazole 
• 5221-68-1 N-Acetonyl-diphenyl-essigsaeure-amid 
• 52829-67-1 2-benzhydryl-5-methyl-oxazole 

Relevant articles and documents

Intramolecular ring closure in N-propynyl-barbituric acids and N-propynyl-benzamides

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Method for treating conditions related to the glutamate receptor using carboxylic acid amide derivatives

The present invention is concerned with the use of carbonylamino derivatives of the formula wherein R signifies lower alkyl, lower alkenyl, lower alkinyl, cycloalkyl, lower alkoxy or CF3; R1signifies hydrogen or lower alkyl; R2and R3signify, independently from each other, hydrogen, halogen or nitro; Y signifies CH or N; n is 0-6; m is 0-2; as well as with their pharmaceutically acceptable salts for the treatment of diseases, which relate to metabotropic glutamate receptor antagonists and/or agonists.