52305-68-7

Basic information

• Product Name: 1,2-Cyclohexanediol, 1-phenyl-
• Synonyms: 1-phenyl-cyclohexanediol-(1.2);1-Phenyl-cyclohexandiol-(1.2);1-phenyl-cyclohexane-1,2-diol;1-phenyl-1,2-cyclohexanediol;1-phenylcyclohexan-1,2-diol;(1.2-Dioxy-cyclohexyl)-benzol
• CAS NO: 52305-68-7
• Molecular Formula: C12H16O2
• Molecular Weight: 192.258
• Mol File: 52305-68-7.mol
• Article Data: 81

Chemical Properties

• Boiling Point: 172 °C (13 mmHg)
• CAS DataBase Reference: 1,2-Cyclohexanediol, 1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Cyclohexanediol, 1-phenyl-(52305-68-7)
• EPA Substance Registry System: 1,2-Cyclohexanediol, 1-phenyl-(52305-68-7)

Safety Data

• Hazardous Substances Data: 52305-68-7(Hazardous Substances Data)

Upstream product

• 771-98-2 1-Phenylcyclohexene 
• 99942-90-2 2-Acetoxy-1-phenyl-cyclohexanol 
• 4829-02-1 2-hydroxy-2-phenylcyclohexanone 
• 5775-23-5 1-phenylcyclohexene oxide 
• 23313-45-3 acetic acid 2-acetoxy-2-phenylcyclohexyl ester 
• 1222099-34-4 (+/-)-2-(2-tolylaminooxy)cyclohexanone 
• 100-58-3 phenylmagnesium bromide 
• 4829-01-0 (-)-(1S,2S)-1-phenylcyclohex-1-ene oxide 
• 100-59-4 phenylmagnesium chloride 
• 533-60-8 cyclohexanone-2-ol 
• 408525-07-5 2-iodo-1-phenyl-cyclohexanol 
• 1161819-40-4 (R)-2-(2-tolylaminooxy)cyclohexanone 
• 4912-59-8 1-phenyl-1,2-cyclohexanediol 
• 4829-01-0 (1R,2R)-1-phenyl-1-cyclohexene oxide 

Downstream Products

• 4912-59-8 (1R,2R)-1-phenyl-1,2-cyclohexanediol 
• 4829-02-1 (S)-(+)-2-hydroxy-2-phenylcyclohexanone 
• 134750-78-0 (-)-trans-4a,20a-Diphenyloctahydro-5,8,11,14,17,20-hexaoxabenzocyclooctadecane 
• 134750-73-5 (-)-cis-2-(Methoxymethoxy)-1-phenylcyclohexanol 
• 134875-74-4 (-)-trans-1,2-diphenylcyclohexane-1,2-diol 
• 134750-77-9 (-)-cis-4a-Phenyloctahydro-5,8,11,14,17,20-hexaoxabenzocyclooctadecane 
• 134750-75-7 2,2'-Oxydiethylenedioxybis(2-phenylcyclohexanol) 
• 134750-74-6 (+)-2,2'-Oxydiethylenedioxybis(2-phenylcyclophenylethyl methyl ether) 
• 124-04-9 Adipic acid 
• 4144-62-1 5-benzoylvaleric acid 
• 1444-65-1 (RS)-2-phenylcyclohexanone 
• 21573-69-3 1-phenyl-1-cyclopentanecarboxaldehyde 
• 27167-34-6 trans-1-Phenylcyclohexane-1,2-diol 
• 4829-02-1 2-hydroxy-2-phenylcyclohexanone 

Relevant articles and documents

Photo-Induced Dihydroxylation of Alkenes with Diacetyl, Oxygen, and Water

Herein reported is a photo-induced production of vicinal diols from alkenes under mild reaction conditions. The present dihydroxylation method using diacetyl (= butane-2,3-dione), oxygen, and water dispenses with toxic reagents and intractable waste generation.

Enantioselective Dihydroxylation of Alkenes Catalyzed by 1,4-Bis(9-O-dihydroquinidinyl)phthalazine-Modified Binaphthyl–Osmium Nanoparticles

A series of unprecedented binaphthyl–osmium nanoparticles (OsNPs) with chiral modifiers were applied in the heterogeneous asymmetric dihydroxylation of alkenes. A remarkable size effect of the OsNPs, depending on the density of the covalent organic shells, on the reactivity and enantioselectivity of the dihydroxylation reaction was revealed. Successful recycling of the OsNPs was also demonstrated and high reaction efficiency and enantioselectivity were maintained.

Regioselective 1,2-Diol Rearrangement by Controlling the Loading of BF3·Et2O and Its Application to the Synthesis of Related Nor-Sesquiterene- and Sesquiterene-Type Marine Natural Products

The regiocontrolled rearrangement of 1,2-diols has been achieved by controlling the loading of BF3·Et2O. Its applicability is showcased by the divergent synthesis of austrodoral, austrodoric acid, and 8-epi-11-nordriman-9-one, as well as a formal synthesis of siphonodictyal B and liphagal. A new light is shed on piancol-type rearrangements that will be useful in diversity-oriented synthesis of related natural products.