52313-59-4

Basic information

• Product Name: 2-CHLORO-6-METHYL-PYRIDINE 1-OXIDE
• Synonyms: 2-CHLORO-6-METHYL-PYRIDINE 1-OXIDE;2-Chloro-6-methyl-1-oxidopyridin-1-ium
• CAS NO: 52313-59-4
• Molecular Formula: C₆H₆ClNO
• Molecular Weight: 143.57094
• Product Categories: alkyl chloride
• Mol File: 52313-59-4.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 60-65 °C(Press: 0.07 Torr)
• Appearance: /
• Density: 1.22±0.1 g/cm3(Predicted)
• PKA: -0.36±0.10(Predicted)
• CAS DataBase Reference: 2-CHLORO-6-METHYL-PYRIDINE 1-OXIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-6-METHYL-PYRIDINE 1-OXIDE(52313-59-4)
• EPA Substance Registry System: 2-CHLORO-6-METHYL-PYRIDINE 1-OXIDE(52313-59-4)

Safety Data

• Hazardous Substances Data: 52313-59-4(Hazardous Substances Data)

Upstream product

• 1824-81-3 2-Amino-6-methylpyridine 
• 100047-37-8 6-Nitro-2-picoline-N-oxide 
• 75-36-5 acetyl chloride 
• 18368-63-3 6-chloro-2-picoline 
• 25063-84-7 2-amino-6-methylpyridine N-oxide 
• 13720-82-6 6-Acetamido-2-picoline-N-oxide 
• 64741-01-1 m-chloroperoxybenzoic acid 

Downstream Products

• 142832-29-9 2-chloro-6-pyridinecarboxylic acid N-oxide 
• 83782-89-2 2-(hydroxymethyl)-6-chloropyridine hydrochloride 
• 253686-25-8 α-fluoro-6-(4-phenylpiperazinyl)-2-picoline N-oxide 
• 54087-03-5 6-chloropyridine-2-carboxaldehyde 
• 83782-48-3 2-<<(p-bromophenyl)thio>methyl>-6-chloropyridine 
• 40314-84-9 2-chloro-6-methyl-4-nitropyridine N-oxide 
• 123926-71-6 2-benzyloxy-6-methyl-pyridine-1-oxide 
• 123926-27-2 2-benzyloxy-6-chloromethylpyridine 
• 198649-49-9 2-benzyloxy-6-hydroxymethylpyridine 
• 1058129-60-4 2-(4-amino-2-butoxy-6-methylpyridin-3-yl)-4-bromo-N,N-diisopropylbenzamide 
• 79055-63-3 2-chloro-6-methylpyridin-4-amine 

Relevant articles and documents

2- [ (2-SUBSTITUTED) -IND0LIZIN-3-YL] -2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS

The invention provides compounds of formula (I), and pharmaceutically acceptable salts thereof wherein: Rl, R2, R3, R4, R5, R6, R7, X and X1 are as defined herein. These compounds are useful in the manufacture of medicaments for use in the prevention or treatment of a fungal disease. Compounds of formula (I), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides.

Probing integrin selectivity: rational design of highly active and selective ligands for the α5β1 and αvβ3 integrin receptor

(Chemical Equation Presented) Try and fit in: A strategy for the rational design of α5β1 ligands for the purpose of lead generation and biochemical studies on integrin selectivity is based α5β1 homology modeling. Ligand 1 can bind α5β1 with activities in

The Reaction of Acetic Acid 2-Selenoxo-2H-pyridin-1-yl Esters with Benzynes: A Convenient Route to Benzo[b]seleno[2,3-b]pyridines

Benzyne and its 3,4,5,6-tetraphenyl, 3- and 4-methyl, 3-methoxy and 4,5-difluoro derivatives react with acetic acid 2-selenoxo-2H-pyridin-1-yl esters 4a-e to give benzo[b]seleno[2,3-b]pyridines 10-15 in modest yields. The benzynes were generated by one or more of the following methods: diazotization of anthranilic acids 5a-g with isoamyl nitrate; mild thermal decomposition of 2-diazoniobenzenecarboxylate hydrochlorides 6a-d; treatment of (phenyl)[o-(trimethylsilyl)phenyl]iodonium triflate (7) with tetrabutylammonium fluoride; and treatment of 2-trimethylsilylphenyl triflates 8a-c with cesium fluoride. In all the reactions, the corresponding 2-(methylselenenyl)pyridines 16a-d were also obtained suggesting that these reactions may involve selenium addition to benzyne via a SET (single electron transfer).