5259-97-2Relevant articles and documents
PROCESS FOR THE SYNTHESIS OF ISOCYANATE-FREE OMEGA-HYDROXY-URETHANES, ALPHA-OMEGA-DIURETHANES AND OLIGO (POLY)URETHANES
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Page/Page column 6-7, (2021/11/26)
The synthesis of omega-hydroxyalkyl-urethanes, and of alfa-omega-diurethanes is reported which includes the reaction of diols with urea in presence of catalysts based on Ce at temperatures between 125 and 170°C over 4-8 h reaction time. A process for the production of oligomers of omega-hydroxyalkyl-urethanes is also reported based on the reaction of urea with diols in presence of Ce or Zr catalysts or Ce mixed oxides at 125-170°C over 4-20 h.
Pd-catalysed oxidative carbonylation of amino alcohols to N,N′-bis(hydroxyalkyl)ureas under mild conditions using molecular oxygen as the oxidant
Giannoccaro, Potenzo,Ferragina, Carla,Gargano, Michele,Quaranta, Eugenio
experimental part, p. 78 - 84 (2010/09/06)
A very simple method has been developed for the selective synthesis of symmetrical N,N′-bis(hydroxyalkyl)ureas, OC[NH-(CH2)x-OH]2 (x = 3-6), by oxidative carbonylation of α,ω-amino alcohols [3-aminopropanol (3-AP), 4-aminobutanol (4-AB), 5-aminopentanol (5-APe), 6-aminohexanol (6-AH)] with CO/O2 mixtures (O2 = 5 mol%) in the presence of Pd(II)/ligand/NEt3·HI catalytic systems. The catalytic process takes place under very mild conditions (p(CO/O2) = 0.1 MPa; 303-333 K). The target products can be isolated in high yield through a very simple and straightforward procedure. The catalytic system can be easily recovered and recycled for several times. The influence of a few reaction parameters (nature of ancillary ligand and iodide co-catalyst, I/Pd molar ratio, etc.) on the catalytic activity has also been investigated and the main mechanistic features of the catalytic process fully elucidated.
Formation of Cyclic Urethanes from Amino Alcohols and Carbon Dioxide Using Phosphorus(III) Reagents and Halogenoalkanes
Kubota, Yasuhiko,Kodaka, Masato,Tomohiro, Takenori,Okuno, Hiroaki (Yohmei)
, p. 5 - 6 (2007/10/02)
Cyclic urethanes are obtained in good yields under mild conditions from amino alcohols and carbon dioxide using phosphorus(III) reagents and halogenoalkanes (CCl4 and CCl3CCl3).
