52916-86-6Relevant articles and documents
Palladium-Catalyzed Two-Component Domino Coupling Reaction of (Z)-β-Bromostyrenes with Norbornenes: Synthesis of 1,5-Enynes
Mao, Jiangang,Li, Huifang,Wen, Herui,Li, Min,Fan, Xiaolin,Bao, Weiliang
, p. 1873 - 1879 (2016)
Polyfunctional molecules, 1,5-enynes, have been achieved via a palladium(0)-catalyzed domino coupling reaction of (Z)-β-bromostyrenes with norbornenes in the presence of cesium carbonate and N,N-dimethylformamide. The process involves a double Heck-type procedure, two-fold C(sp2) H activation and formation of two carbon-carbon bonds. There are possibilities of diversified transformation for the domino coupling of (Z)-β-bromostyrenes with norbornenes, the procedure is successfully driven to 1,5-enynes via accurate adjustment of the reaction conditions. (Figure presented.) .
Method for synthesizing alpha,beta-dibromide
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Paragraph 0056; 0057; 0058, (2018/04/01)
The invention discloses a method for synthesizing alpha,beta-dibromide. The method is characterized in that a styrene compound as shown in the formula I is taken as a raw material, Zn-Al hydrotalciteZnAl-BrO3-LDHs of a bromate intercalation is taken as
Palladium(0)-Catalyzed Methylcyclopropanation of Norbornenes with Vinyl Bromides and Mechanism Study
Mao, Jiangang,Xie, Hujun,Bao, Weiliang
, p. 3678 - 3681 (2015/08/18)
An unusual methylcyclopropanation from [2 + 1] cycloadditions of vinyl bromides to norbornenes catalyzed by Pd(OAc)2/PPh3 in the presence of CH3ONa and CH3OH has been established. A methylcyclopropane subunit was installed by a 3-fold domino procedure involving a key protonation course. Preliminary deuterium-labeling studies revealed that the proton came from methyl of CH3OH and also exposed an additional hydrogen/deuterium exchange process. These two proton-concerned reactions were fully chemoselective.