60655-80-3 Usage
Description
(E)-1-(2-Bromovinyl)-4-methylbenzene, also known as 4-methyl-alpha-bromo styrene, is a chemical compound with the molecular formula C9H9Br. It is a derivative of styrene featuring a bromine atom attached to the carbon atom at position 2 in the styrene ring, and a vinyl group (C=C double bond) at position 1. (E)-1-(2-Bromovinyl)-4-methylbenzene is recognized for its utility as a building block in the synthesis of various organic compounds, particularly within the realm of organic chemistry.
Uses
Used in Organic Chemistry:
(E)-1-(2-Bromovinyl)-4-methylbenzene is used as a building block for the synthesis of various organic compounds due to its unique structure and reactivity. Its application in this field is crucial for creating new molecules with specific properties and functions.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, (E)-1-(2-Bromovinyl)-4-methylbenzene is used as a reagent for the production of various pharmaceuticals. Its role in creating the molecular structures of drugs makes it a valuable component in drug development.
Used in Agrochemical Production:
(E)-1-(2-Bromovinyl)-4-methylbenzene also finds application in the agrochemical sector, where it is utilized in the synthesis of compounds used in agriculture, such as pesticides and fertilizers, to enhance crop protection and yield.
Used in the Development of New Materials:
(E)-1-(2-Bromovinyl)-4-methylbenzene may have potential applications in the development of new materials, given its unique chemical structure. This could include materials with specific properties for use in various industries, such as electronics or aerospace.
Used in the Creation of Biologically Active Compounds:
Furthermore, (E)-1-(2-Bromovinyl)-4-methylbenzene may be employed in the creation of biologically active compounds, which could have implications in the fields of medicine and biotechnology.
Safety Note:
It is important to handle (E)-1-(2-Bromovinyl)-4-methylbenzene with caution, as it may pose health and safety hazards if not properly managed. Appropriate safety measures should be taken during its use to minimize risks.
Check Digit Verification of cas no
The CAS Registry Mumber 60655-80-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,6,5 and 5 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 60655-80:
(7*6)+(6*0)+(5*6)+(4*5)+(3*5)+(2*8)+(1*0)=123
123 % 10 = 3
So 60655-80-3 is a valid CAS Registry Number.
60655-80-3Relevant articles and documents
Skeletally Tunable Seven-Membered-Ring Fused Pyrroles
Andreou, Dimitrios,Essien, Nsikak B.,Pubill-Ulldemolins, Cristina,Terzidis, Michael A.,Papadopoulos, Athanasios N.,Kostakis, George E.,Lykakis, Ioannis N.
supporting information, p. 6685 - 6690 (2021/09/11)
We describe a copper-mediated method that enables the synthesis of seven-membered-ring fused pyrroles (7-mrFPs). The protocol proceeds via an in situ spiro-intermediate ring expansion and tolerates a library of 7-mrFP derivatives with a broad range of functional groups in a simple step with tangible parameters and substrate adaptations. These rare 7-mrFPs are now accessible on a millimolar scale, and selected examples exhibit high antioxidant activity.
Illuminatinganti-hydrozirconation: controlled geometric isomerization of an organometallic species
Gilmour, Ryan,Hostmann, Theresa,Nevesely, Tomá?
, p. 10643 - 10648 (2021/08/20)
A general strategy to enable the formalanti-hydrozirconation of arylacetylenes is reported that mergescis-hydrometallation using the Schwartz Reagent (Cp2ZrHCl) with a subsequent light-mediated geometric isomerization atλ= 400 nm. Mechanistic delineation of thecontra-thermodynamic isomerization step indicates that a minor reaction product functions as an efficientin situgenerated photocatalyst. Coupling of theE-vinyl zirconium species with an alkyne unit generates a conjugated diene: this has been leveraged as a selective energy transfer catalyst to enableE→Zisomerization of an organometallic species. Through anUmpolungmetal-halogen exchange process (Cl, Br, I), synthetically useful vinyl halides can be generated (up toZ?:?E= 90?:?10). This enabling platform provides a strategy to access nucleophilic and electrophilic alkene fragments in both geometric forms from simple arylacetylenes.
A Simplified Protocol for the Stereospecific Nickel-Catalyzed C-S Vinylation Using NiX 2 Salts and Alkyl Phosphites
Larin, Egor M.,Lautens, Mark,Marchese, Austin D.,Mirabi, Bijan
, p. 311 - 319 (2019/12/28)
A Ni-catalyzed C-S cross-coupling using only NiI 2 (0.5-2.5 molpercent) and P(O i Pr) 3 (2.0-10.0 molpercent) is reported. Using an air-stable Ni(II) precatalyst, and a cheap and commercially available ligand, a scalable and robust method was developed to cross-couple various thiophenols and styryl bromides, including some sterically encumbered thiols, an α-bromocinnamaldehyde as well as a thiolation-cyclization.
