5331-28-2

Basic information

• Product Name: 1-TERT-BUTYL-4-PHENOXY-BENZENE
• Synonyms: 1-TERT-BUTYL-4-PHENOXY-BENZENE;1-Phenoxy-4-tert-butylbenzene;4-tert-Butyldiphenyl ether;4-tert-Butylphenylphenyl ether;Phenyl 4-tert-butylphenyl ether;Phenyl(4-tert-butylphenyl) ether
• CAS NO: 5331-28-2
• Molecular Formula: C₁₆H₁₈O
• Molecular Weight: 226.31352
• Mol File: 5331-28-2.mol
• Article Data: 50

Chemical Properties

• Boiling Point: 307.1°Cat760mmHg
• Flash Point: 135.1°C
• Appearance: /
• Density: 0.998g/cm³
• Vapor Pressure: 0.00134mmHg at 25°C
• Refractive Index: 1.539
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-TERT-BUTYL-4-PHENOXY-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-TERT-BUTYL-4-PHENOXY-BENZENE(5331-28-2)
• EPA Substance Registry System: 1-TERT-BUTYL-4-PHENOXY-BENZENE(5331-28-2)

Safety Data

• Hazardous Substances Data: 5331-28-2(Hazardous Substances Data)

Usage

Chemical class

Benzene

Usage

Widely used in the production of various industrial and consumer products

Characterized by

Presence of a tert-butyl group and a phenoxy group attached to a benzene ring

Chemical and physical properties

Unique due to the presence of the tert-butyl and phenoxy groups

Uses

Precursor in the synthesis of other organic compounds, intermediate in the production of fragrances, dyes, and polymers, potential use in pharmaceutical applications.

InChI:InChI=1/C16H18O/c1-16(2,3)13-9-11-15(12-10-13)17-14-7-5-4-6-8-14/h4-12H,1-3H3

Upstream product

• 107-39-1 2,4,4-trimethyl-1-pentene 
• 101-84-8 diphenylether 
• 507-20-0 tertiary butyl chloride 
• 78-83-1 2-methyl-propan-1-ol 
• 108-86-1 bromobenzene 
• 98-54-4 para-tert-butylphenol 
• 28899-97-0 triphenylbismuth(V) diacetate 
• 83566-43-2 tetraphenyl-bismuth trifluoroacetate 
• 3972-65-4 1-bromo-4-tert-butylbenzene 
• 108-95-2 phenol 
• 98-80-6 phenylboronic acid 
• 7664-93-9 sulfuric acid 
• 7446-70-0 aluminium trichloride 
• 35779-04-5 1-tert-butyl-4-iodobenzene 

Downstream Products

• 98-54-4 para-tert-butylphenol 
• 71-43-2 benzene 
• 253185-03-4 tert-butylbenzene 
• 108-95-2 phenol 
• 1821-36-9 N-phenyl-2-cyclohexylamine 
• 101-84-8 diphenylether 
• 28530-41-8 4-phenoxy-1-isopropylbenzene 
• 4167-74-2 4-isobutylphenol 
• 1706-12-3 4-phenoxytoluene 
• 36207-23-5 1-ethyl-4-phenoxybenzene 
• 34349-75-2 4-isobutyldiphenyl oxide 

Relevant articles and documents

Ligand- and Counterion-Assisted Phenol O-Arylation with TMP-Iodonium(III) Acetates

High reactivity of trimethoxyphenyl (TMP)-iodonium(III) acetate for phenol O-arylation was achieved. It was first determined that the TMP ligand and acetate anion cooperatively enhance the electrophilic reactivity toward phenol oxygen atoms. The proposed method provides access to various diaryl ethers in significantly higher yields than the previously reported techniques. Various functional groups, including aliphatic alcohol, boronic ester, and sterically hindered groups, were tolerated during O-arylation, verifying the applicability of this ligand- and counterion-assisted strategy.

Aromatic ether compound or the sulfhydryl compound

[Problem] Aromatic ether compounds and aromatic sulfide compound of this new technology to[Solution] In general formula (1a), (1b), (1c) palladium or nickel compound or a phosphine compound represented by the compound comprising a transition metal compound in the presence of a transition metal catalyst, (A1) is represented by compounds having hydroxy carbon C a-OH or (A2) with a compound represented by the sulfhydryl carbon C a-SH, nitro group (- NO2 ) To react with an aromatic nitro compound (B), (A1) to the compound of the aromatic nitro compound (C1) or the reaction product of an aromatic ether compounds (B) hetero coupling (A2) of the compounds of the reaction product of an aromatic sulfide compound of an aromatic nitro compound (C2) generating (B) hetero coupling characterized by comprising the step of, aromatic ether compounds or aromatic sulfide compound. [Drawing] no

URJC-1-MOF as New Heterogeneous Recyclable Catalyst for C-Heteroatom Coupling Reactions

Guillermo Calleja and co-workers from @urjc describe URJC-1-MOF as a new heterogeneous recyclable catalyst for c-heteroatom coupling reactions. The capacity of copper-based URJC-1-MOF as a MOF catalyst in cross-coupling reactions has been evaluated, focusing on the Chan-Lam-Evans arylation-type reactions on amines and alcohols without extra additives or ligands. The extraordinary chemical and structural stability of URJC-1-MOF and its good specific surface, make this material a promising alternative to homogeneous Cu (II) catalysts for cross-coupling reactions. URJC-1-MOF showed a remarkable catalytic activity for cross-coupling C?N and C?O reactions, higher than other heterogeneous and homogeneous copper-based catalyst, such as CuO, HKUST-1, Cu?MOF-74, Cu(OAc)2 and CuSO4?5H2O. Moreover, its easy recovery by simple filtration and reusability in successive runs without any loss of activity and stability, demonstrates the potential of URJC-1-MOF as an alternative catalyst for this kind of reactions in different chemical media of industrial interest.