53365-80-3

Basic information

• Product Name: 2-BENZYL 4-(TERT-BUTYL) 3-(3-METHOXY-3-OXOPROPYL)-5-METHYL-1H-PYRROLE-2,4-DICARBOXYLATE
• Synonyms: 2-BENZYL 4-(TERT-BUTYL) 3-(3-METHOXY-3-OXOPROPYL)-5-METHYL-1H-PYRROLE-2,4-DICARBOXYLATE
• CAS NO: 53365-80-3
• Molecular Formula: C₂₂H₂₇NO₆
• Molecular Weight: 401.45
• Mol File: 53365-80-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 556.6°Cat760mmHg
• Flash Point: 290.4°C
• Appearance: /
• Density: 1.182g/cm³
• Vapor Pressure: 2E-12mmHg at 25°C
• Refractive Index: 1.549
• CAS DataBase Reference: 2-BENZYL 4-(TERT-BUTYL) 3-(3-METHOXY-3-OXOPROPYL)-5-METHYL-1H-PYRROLE-2,4-DICARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZYL 4-(TERT-BUTYL) 3-(3-METHOXY-3-OXOPROPYL)-5-METHYL-1H-PYRROLE-2,4-DICARBOXYLATE(53365-80-3)
• EPA Substance Registry System: 2-BENZYL 4-(TERT-BUTYL) 3-(3-METHOXY-3-OXOPROPYL)-5-METHYL-1H-PYRROLE-2,4-DICARBOXYLATE(53365-80-3)

Safety Data

• Hazardous Substances Data: 53365-80-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C22H27NO6/c1-14-18(20(25)29-22(2,3)4)16(11-12-17(24)27-5)19(23-14)21(26)28-13-15-9-7-6-8-10-15/h6-10,23H,11-13H2,1-5H3

Upstream product

• 1694-31-1 tert-butyl acetoacetate 
• 74839-04-6 2-[(E)-Hydroxyimino]-3-oxo-hexanedioic acid 1-benzyl ester 6-methyl ester 
• 53314-75-3 Benzyl-δ-(methoxycarbonyl)-γ-oxovalerate 

Downstream Products

• 53365-81-4 3-(2-methoxycarbonyl-ethyl)-5-methyl-pyrrole-2,4-dicarboxylic acid 2-benzyl ester 
• 183061-79-2 C₄₄H₅₁N₃O₁₇ 
• 135100-99-1 (S)-4-<5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl>-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-9-(2,2,2-tribromoethoxycarbonyl)-4,5-dihydrodipyrrin-1(10H)-one 
• 135100-95-7 (R)-4-<5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl>-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-9-(2,2,2-tribromoethoxycarbonyl)-4,5-dihydrodipyrrin-1(10H)-one 
• 183005-13-2 4-Iodo-3-(2-methoxycarbonyl-ethyl)-5-methyl-1H-pyrrole-2-carboxylic acid benzyl ester 
• 183005-14-3 4-Carboxymethyl-3-(2-methoxycarbonyl-ethyl)-5-methyl-1H-pyrrole-2-carboxylic acid benzyl ester 
• 183005-06-3 3-(2-Methoxycarbonyl-ethyl)-5-methyl-4-(2-trimethylsilanyl-ethoxycarbonylmethyl)-1H-pyrrole-2-carboxylic acid benzyl ester 
• 183005-15-4 5-Acetoxymethyl-3-(2-methoxycarbonyl-ethyl)-4-(2-trimethylsilanyl-ethoxycarbonylmethyl)-1H-pyrrole-2-carboxylic acid benzyl ester 
• 183005-05-2 5-[3-Carboxymethyl-4-(2-methoxycarbonyl-ethyl)-2-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-ylmethyl]-4-(2-methoxycarbonyl-ethyl)-3-methoxycarbonylmethyl-1H-pyrrole-2-carboxylic acid benzyl ester 
• 183005-10-9 4-(2-Methoxycarbonyl-ethyl)-5-[4-(2-methoxycarbonyl-ethyl)-2-methyl-5-oxo-3-(2-trimethylsilanyl-ethoxycarbonylmethyl)-2,5-dihydro-1H-pyrrol-2-ylmethyl]-3-methoxycarbonylmethyl-1H-pyrrole-2-carboxylic acid benzyl ester 
• 135100-96-8 4-[5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-methoxycarbonylmethylpyrrol-2-ylmethyl]-7-carboxymethyl-2,8-bis(2-methoxycarbonylethyl)-9-(2,2,2-tribromoethoxycarbonyl)-3-(2-trimethylsilylethoxycarbonylmethyl)-4,5-dihydrodipyrrin-1(10H)-one 
• 135100-97-9 4-[5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-methoxycarbonylmethylpyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-7-methoxycarbonylmethyl-9-(2,2,2-tribromoethoxycarbonyl)-3-(2-trimethylsilylethoxycarbonylmethyl)-4,5-dihydrodipyrrin-1(10H)-one 

Relevant articles and documents

Biosynthesis of porphyrins and related macrocycles. Part 44. Synthetic and stereochemical studies on the proposed spiro intermediate for biosynthesis of the natural porphyrins

A route is devised for synthesis of both enantiomers of the spiro lactam 4. The enzyme uroporphyrinogen III synthase (cosynthetase), which converts hydroxymethylbilane 1 into uroporphyrinogen III 3, is competitively inhibited more than twenty times more s