53412-38-7

Basic information

• Product Name: 6-HYDROXY-2H-1,4-BENZOXAZIN-3(4H)-ONE
• Synonyms: 6-HYDROXY-2H-1,4-BENZOXAZIN-3(4H)-ONE;6-Hydroxy-3,4-dihydro-2H-1,4-benzoxazin-3-one;6-Hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazine;6-Hydroxy-4H-benzo[1,4]oxazin-3-one;6-hydroxy-2H-benzo[b][1,4]oxazin-3(4H)-one;6-hydroxy-4H-1,4-benzoxazin-3-one
• CAS NO: 53412-38-7
• Molecular Formula: C₈H₇NO₃
• Molecular Weight: 165.15
• Mol File: 53412-38-7.mol
• Article Data: 11

Chemical Properties

• Melting Point: 267-270℃
• Boiling Point: 432.0±45.0 °C(Predicted)
• Appearance: /
• Density: 1.396±0.06 g/cm3(Predicted)
• PKA: 9.61±0.20(Predicted)
• CAS DataBase Reference: 6-HYDROXY-2H-1,4-BENZOXAZIN-3(4H)-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-HYDROXY-2H-1,4-BENZOXAZIN-3(4H)-ONE(53412-38-7)
• EPA Substance Registry System: 6-HYDROXY-2H-1,4-BENZOXAZIN-3(4H)-ONE(53412-38-7)

Safety Data

• Hazardous Substances Data: 53412-38-7(Hazardous Substances Data)

Usage

General Description

6-HYDROXY-2H-1,4-BENZOXAZIN-3(4H)-ONE, also known as DIMBOA-Glc, is a plant secondary metabolite that belongs to the benzoxazinoid group of compounds. It is primarily found in several cereal crops, such as maize, wheat, and rye, and plays a key role in the defense mechanisms of these plants against herbivores and pathogens. DIMBOA-Glc has been shown to exhibit strong antifungal and anti-herbivore properties, making it an important chemical for plant protection. Additionally, it has been studied for its potential health benefits, including anti-inflammatory and anti-cancer properties. Overall, 6-HYDROXY-2H-1,4-BENZOXAZIN-3(4H)-ONE is a valuable chemical compound with potential applications in both agriculture and medicine.

Upstream product

• 22158-78-7 2-chloro-N-(2',5'-dimethoxyphenyl)acetamide 
• 102580-34-7 2-chloro-N-(2,5-dihydroxyphenyl)acetamide 
• 33252-98-1 6-propionyloxy-4H-benzo[1,4]oxazin-3-one 
• 89441-85-0 6-acetoxy-2H-1,4-benzoxazin-3(4H)-one 
• 33252-96-9 4-acetoxy-(2H)-1,4-benzoxazin-3(4H)-one 
• 5466-88-6 3,4-dihydro-3-oxo-2H-1,4-benzoxazine 
• 37682-31-8 ethyl o-nitrophenoxyacetate 
• 771-26-6 4-hydroxy-2H-1,4-benzoxazin-3-one 
• 102-56-7 2,5-dimethoxyaniline 
• 5023-12-1 6-methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one 
• 20734-76-3 2-amino-4-methoxyphenol 

Downstream Products

• 33252-97-0 6-benzoyloxy-4H-benzo[1,4]oxazin-3-one 
• 53412-42-3 N-acetyl-3,5-dinitro-O-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-L-tyrosine methyl ester 
• 5023-12-1 6-methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one 
• 6238-92-2 [2-(3,4-Dichloro-benzoylamino)-4-hydroxy-phenoxy]-acetic acid 
• 26021-57-8 3,4-dihydro-6-hydroxy-1,4(2H)-benzoxazine 

Relevant articles and documents

OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING

This invention concerns novel oxazine-based fluorophore compounds useful in invivo nerve imaging, as well as compositions comprising them and methods for their use.

NEAR-INFRARED NERVE-SPARING FLUOROPHORES

Provided are far red to near-infrared nerve-sparing fluorescent compounds, compositions comprising them, and methods of their use in medical procedures.

ACTIVATIBLE DYES

Novel, activatable dyes, such as photoactivatable dyes, e.g., oxazine dyes, are described. Some of the dyes are targeting dyes that can, e.g., target biomolecules, such as polypeptides, proteins, or nucleic acids. Upon activation, such as by irradiation, the novel dyes rapidly turn on their fluorescence and emit light, such as near-IR light with spatial and temporal precision.