53689-84-2

Basic information

• Product Name: Ethanone, 1-(4-benzoylphenyl)-
• Synonyms: 1-(4-benzoylphenyl)ethan-1-one;4-Acetyl-benzophenon;1-(4-benzoylphenyl) ethanone;4-acetyl-benzophenone;4-acetobenzophenone;Ethanone,1-(4-benzoylphenyl)
• CAS NO: 53689-84-2
• Molecular Formula: C15H12O2
• Molecular Weight: 224.259
• Mol File: 53689-84-2.mol
• Article Data: 108

Chemical Properties

• Melting Point: 83-84 °C
• Boiling Point: 383.7±25.0 °C(Predicted)
• Density: 1.126±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Ethanone, 1-(4-benzoylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(4-benzoylphenyl)-(53689-84-2)
• EPA Substance Registry System: Ethanone, 1-(4-benzoylphenyl)-(53689-84-2)

Safety Data

• Hazardous Substances Data: 53689-84-2(Hazardous Substances Data)

Upstream product

• 13329-40-3 4-Iodoacetophenone 
• 201230-82-2 carbon monoxide 
• 98-80-6 phenylboronic acid 
• 109613-00-5 4-acetophenyl triflate 
• 586-89-0 4-acetyl-benzoic acid 
• 100-52-7 benzaldehyde 
• 99-90-1 para-bromoacetophenone 
• 764-48-7 ethyleneglycol vinyl ether 
• 134-85-0 4-chlorobenzophenone 
• 1942-31-0 4-(phenylethinyl)acetophenone 
• 6136-66-9 4-iodobenzophenone 
• 65189-90-4 4-(1-hydroxyethyl)benzophenone 
• 22543-70-0 α-(p-ethylphenyl)-α-phenylmethanol 
• 63468-90-6 phenylglyoxylic acid potassium salt 

Downstream Products

• 26077-80-5 (4-benzoylphenyl)acetic acid 
• 94705-09-6 (4-acetylphenyl)(phenyl)methanol 
• 85696-44-2 4-(1-Hydroxyethyl)benzophenone 
• 1134395-07-5 C₁₈H₁₄N₂OS 
• 611-95-0 4-carboxybenzophenone 
• 24021-68-9 methyl 4-benzoylbenzeneacetate 
• 78212-11-0 (+/-)-[4-(α-hydroxy-benzyl)-phenyl]-acetic acid 
• 620-85-9 1-benzyl-4-ethylbenzene 
• 93986-36-8 4-benzoyl-α-chloroacetophenone 

Relevant articles and documents

Aromatization as an Impetus to Harness Ketones for Metallaphotoredox-Catalyzed Benzoylation/Benzylation of (Hetero)arenes

Herein we report ketones as feedstock materials in radical cross-coupling reactions under Ni/photoredox dual catalysis. In this approach, simple condensation first converts ketones into prearomatic intermediates that then act as activated radical sources for cross-coupling with aryl halides. Our strategy enables the direct benzylation/benzoylation of (hetero)arenes under mild reaction conditions with high functional group tolerance.

Pd-Catalysed carbonylative Suzuki-Miyaura cross-couplings using Fe(CO)5under mild conditions: generation of a highly active, recyclable and scalable ‘Pd-Fe’ nanocatalyst

The dual function and role of iron(0) pentacarbonyl [Fe(CO)5] has been identified in gaseous CO-free carbonylative Suzuki-Miyaura cross-couplings, in which Fe(CO)5supplied COin situ, leading to the propagation of catalytically active Pd-Fe nanoparticles. Compared with typical carbonylative reaction conditions, CO gas (at high pressures), specialised exogenous ligands and inert reaction conditions were avoided. Our developed reaction conditions are mild, do not require specialised CO high pressure equipment, and exhibit wide functional group tolerance, giving a library of biaryl ketones in good yields.

Photoinduced Acetylation of Anilines under Aqueous and Catalyst-Free Conditions

A green and efficient visible-light induced functionalization of anilines under mild conditions has been reported. Utilizing nontoxic, cost-effective, and water-soluble diacetyl as photosensitizer and acetylating reagent, and water as the solvent, a variety of anilines were converted into the corresponding aryl ketones, iodides, and bromides. With advantages of environmentally friendly conditions, simple operation, broad substrate scope, and functional group tolerance, this reaction represents a valuable method in organic synthesis.