53795-94-1

Basic information

• Product Name: DL-ALANINE-3,3,3-D3
• Synonyms: DL-ALANINE-3,3,3-D3;DL-ALANINE-3,3,3-D3, 99.5 ATOM % D;DL-Alanine-d3
• CAS NO: 53795-94-1
• Molecular Formula: C3H4D3NO2
• Molecular Weight: 92.11
• Product Categories: Amino Acids 13C, 2H, 15N;A;Alphabetical Listings;Stable Isotopes
• Mol File: 53795-94-1.mol
• Article Data: 7

Chemical Properties

• Melting Point: 289 °C (dec.)(lit.)
• Boiling Point: 212.9°C at 760 mmHg
• Flash Point: 82.6°C
• Appearance: /
• Density: 1.2g/cm³
• Vapor Pressure: 0.0661mmHg at 25°C
• Refractive Index: 1.459
• CAS DataBase Reference: DL-ALANINE-3,3,3-D3(CAS DataBase Reference)
• NIST Chemistry Reference: DL-ALANINE-3,3,3-D3(53795-94-1)
• EPA Substance Registry System: DL-ALANINE-3,3,3-D3(53795-94-1)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 53795-94-1(Hazardous Substances Data)

Usage

General Description

DL-Alanine-3,3,3-D3 is a stable isotope-labeled form of DL-alanine, a non-essential amino acid that is important for protein synthesis and energy production. DL-ALANINE-3,3,3-D3 is used as a biochemical research tool in isotopic labeling studies, metabolic research, and protein structure analysis. It is also utilized in the development of pharmaceuticals and medical diagnostics. The "3,3,3-D3" designation indicates that the compound has three deuterium atoms, a stable heavy isotope of hydrogen, replacing three hydrogen atoms in the alanine molecule. This isotopic labeling allows for the tracking and tracing of the metabolic and biochemical pathways involving alanine in living organisms.

InChI:InChI=1/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/i1D3

Upstream product

• 56-41-7 L-alanin 
• 68006-61-1 pyruvic-d3 acid 
• 18806-29-6 L-alanine-d4 

Downstream Products

• 53795-94-1 L-alanine-d₇ 
• 1467710-09-3 (S)-2-(((benzyloxy)carbonyl)amino)[1,2,3-¹³C₃, 2,3,3,3-²H_4]propanoic acid 
• 352438-84-7 2-aminopropan-1,1,2,3,3,3-d6-1-ol 

Relevant articles and documents

RATIONAL SYNTHESIS OF DEUTERIUM-LABELLED PYRIDOXAL AND PYRIDOXAL ALKALOIDS

A synthesis of pyridoxal is described, which avoids delicate redox reactions at the accomplished pyridoxyl system.This synthesis allows the facile preparation of highly (>98percent) deuterated pyridoxal 10b and of B6-derived alkaloids.

Synthetic method of stable isotope deuterium-labeled alpha-amino acid

The invention relates to a synthetic method of stable isotope deuterium-labeled alpha-amino acid. According to the method, one or more deuterium-labeled halides are taken as labeled precursors and subjected to a reaction with phthalimide dimethyl malonate sodium salt, one or more deuterium-substituted phthalimide dimethyl malonate is obtained, and after hydrolysis, stable isotope deuterium-labeledalpha-amino acid is obtained. Compared with the prior art, the synthetic method is simple, safe and reliable, chemical purity of a product after simple separation and purification reaches 99% or higher, isotope abundance is 99% or higher, and the method can be applied to fields of protein metabolism tracing, food safety testing and the like.

The CFTA method: A reliable procedure for the determination of the absolute configuration of chiral primary amines by 1H NMR spectroscopic analysis

Surprisingly stable anti-periplanar conformers of CFTA amides form the basis of a new and very reliable method for determining the absolute configuration of chiral primary amines by 1H NMR spectroscopy (see picture). CFTA = α-cyano-α-fluoro-p-tolylacetic acid. (Chemical Equation Presented).