5381-80-6

Basic information

• Product Name: threo-1,3-diphenylpropane-1,2-diol
• CAS NO: 5381-80-6
• Molecular Weight: 228.291
• Mol File: 5381-80-6.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: threo-1,3-diphenylpropane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: threo-1,3-diphenylpropane-1,2-diol(5381-80-6)
• EPA Substance Registry System: threo-1,3-diphenylpropane-1,2-diol(5381-80-6)

Safety Data

• Hazardous Substances Data: 5381-80-6(Hazardous Substances Data)

Upstream product

• 56363-42-9 1,2-dibromo-1,3-diphenyl-propane 
• 7570-85-6 trans-2,3-epoxy-1,3-diphenyl-1-propanone 
• 94-41-7 benzalacetophenone 
• 64-17-5 ethanol 
• 41049-36-9 1-hydroxy-1,3-diphenylacetone 
• 23464-17-7 1,3-diphenylpropane-1,2-dione 
• 3412-44-0 (1E)-1,3-diphenylpropene 
• 69897-44-5 trans-(2S,3R)-epoxy-1,3-diphenylpropan-1-one 
• 3412-44-0 1,3-diphenylpropene 
• 170277-50-6 2-benzyl-3-phenyloxirane 
• 60-29-7 diethyl ether 
• 5411-12-1 chalcone epoxide 
• 65095-03-6 trans-1,2-epoxy-1,3-diphenylpropane 
• 122-78-1 phenylacetaldehyde 

Downstream Products

• 102-04-5 1,3-Diphenylpropanone 
• 5381-92-0 1,3-diphenylpropan-2-ol 
• 5381-81-7 (1RS,2SR)-1,2-bis-benzoyloxy-1,3-diphenyl-propane 

Relevant articles and documents

Substrate and inhibitor selectivity, and biological activity of an epoxide hydrolase from Trichoderma reesei

Epoxide hydrolases (EHs) are present in all living organisms and catalyze the hydrolysis of epoxides to the corresponding vicinal diols. EH are involved in the metabolism of endogenous and exogenous epoxides, and thus have application in pharmacology and biotechnology. In this work, we describe the substrates and inhibitors selectivity of an epoxide hydrolase recently cloned from the filamentous fungus Trichoderma reesei QM9414 (TrEH). We also studied the TrEH urea-based inhibitors effects in the fungal growth. TrEH showed high activity on radioative and fluorescent surrogate and natural substrates, especially epoxides from docosahexaenoic acid. Using a fluorescent surrogate substrate, potent inhibitors of TrEH were identified. Interestingly, one of the best compounds inhibit up to 60% of T. reesei growth, indicating an endogenous role for TrEH. These data make TrEH very attractive for future studies about fungal metabolism of fatty acids and possible development of novel drugs for human diseases.

Reduction of carbonyl compounds to their corresponding of alcohols with [Zn(BH4)2(2-MeOpy)] & [Zn(BH4) 2(2-Mepy)] as new reducing agents (a comparison study)

The reduction of a variety of carbonyl compounds was efficiently carried out with [Zn(BH4)2(2-MeOpy)] and [Zn(BH4) 2(2-Mepy)] as new reducing agents. The reduction reactions were performed to give the corresponding alcohols derivatives in perfect yields.

Reduction of α-diketones and acyloins with Zn(BH4) 2/ZrCl4 to their corresponding vicinal diols

α-diketones and acyloins are reduced to the corresponding vicinal diols with Zn(BH4)2/ZrCl4 system in THF at room temperature.