5469-25-0 Usage
Description
(2E)-2-ethylbut-2-enedioic acid, also known as ethylidenemalonate, is a colorless liquid with a fruity odor and the molecular formula C6H8O4. This unsaturated dicarboxylic acid is commonly used as a building block in organic synthesis and can be found in some natural products such as wines and fruits.
Uses
Used in Organic Synthesis:
(2E)-2-ethylbut-2-enedioic acid is used as a building block in organic synthesis for its versatile reactivity and ability to form various compounds.
Used in Pharmaceutical Production:
(2E)-2-ethylbut-2-enedioic acid is used as an intermediate in the production of pharmaceuticals, agrochemicals, and polymers due to its chemical properties and reactivity.
Used in Food Industry:
(2E)-2-ethylbut-2-enedioic acid is used as a flavoring agent in the food industry, providing a fruity aroma and taste to various products.
Used in Fragrance and Dye Production:
(2E)-2-ethylbut-2-enedioic acid is used as a chemical intermediate for the production of fragrances and dyes, contributing to the development of various scent and color compounds.
Used in Anti-inflammatory and Anti-cancer Research:
(2E)-2-ethylbut-2-enedioic acid has been studied for its potential anti-inflammatory and anti-cancer properties, indicating its potential use in the development of therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 5469-25-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,6 and 9 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5469-25:
(6*5)+(5*4)+(4*6)+(3*9)+(2*2)+(1*5)=110
110 % 10 = 0
So 5469-25-0 is a valid CAS Registry Number.
5469-25-0Relevant articles and documents
Asymmetric synthesis of 2-substituted butane-1,4-diols by hydrogenation of homochiral fumaramide derivatives
Jawaid, Samaila,Farrugia, Louis J.,Robins, David J.
, p. 3979 - 3988 (2007/10/03)
Diastereoselective hydrogenation of homochiral fumaramides 1 derived from (2R)-Oppolzer's sultam was observed by analysis of the 1H NMR spectra of the succinamide mixtures with de's of 77-88%. Reduction of these succinamides using LiAlH4 gave the corresponding (2S)-butane-1,4- diols and established that addition of hydrogen takes place selectively on the re-face of fumaramides 1. The stereoselectivity was confirmed by estimating the ee's from the 19F NMR spectra of the Mosher's diesters of the diols. This methodology was applied to the synthesis of selected pyrrolidine natural products in homochiral form.
Purification and properties of crystalline 3-methylaspartase from two facultative anaerobes, Citrobacter sp. strain YG-0504 and Morganella morganii strain YG-0601
Kato,Asano
, p. 93 - 99 (2007/10/02)
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Mechanism of the Enzymic Elimination of Ammonia from 3-Substituted Aspartic Acids by 3-Methylaspartase
Botting, Nigel P.,Akhtar, Mahmoud,Cohen, Mark A.,Gani, David
, p. 1371 - 1373 (2007/10/02)
Kinetic experiments with 3-methylaspartase, using aspartic, 3-methylaspartic, and 3-ethylaspartic acid and the appropriate C-3 deuteriated isotopomers as substrates, reveal that C(3)-H bond cleavage is partially rate-limiting for 3-methylaspartic acid, much less rate-limiting for 3-ethylaspartic acid, and not rate-limiting at all for aspartic acid.
