55605-27-1

Basic information

• Product Name: (4-bromophenyl)methanediyl diacetate
• Synonyms: (4-Bromophenyl)methylene diacetate; methanediol, 1-(4-bromophenyl)-, diacetate
• CAS NO: 55605-27-1
• Molecular Formula: C₁₁H₁₁BrO₄
• Molecular Weight: 287.1066
• Mol File: 55605-27-1.mol
• Article Data: 63

Chemical Properties

• Boiling Point: 340°C at 760 mmHg
• Flash Point: 159.4°C
• Density: 1.467g/cm³
• Vapor Pressure: 8.87E-05mmHg at 25°C
• Refractive Index: 1.535
• CAS DataBase Reference: (4-bromophenyl)methanediyl diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (4-bromophenyl)methanediyl diacetate(55605-27-1)
• EPA Substance Registry System: (4-bromophenyl)methanediyl diacetate(55605-27-1)

Safety Data

• Hazardous Substances Data: 55605-27-1(Hazardous Substances Data)

Upstream product

• 106-38-7 para-bromotoluene 
• 108-24-7 acetic anhydride 
• 1122-91-4 4-bromo-benzaldehyde 
• 18620-02-5 (4-bromophenyl)magnesium bromide 
• 108-59-8 malonic acid dimethyl ester 

Downstream Products

• 1122-91-4 4-bromo-benzaldehyde 
• 58928-91-9 2-(4-bromophenyl)-1,3-dithiane 
• 106650-98-0 1-(4-bromophenyl)but-3-en-1-ol 
• 35583-17-6 3,9-bis(4-bromophenyl)-2,4,8,10-tetraoxaspiro[5.5]undecane 
• 83521-65-7 2-(4-bromophenyl)-1,3-dithiolane 
• 72571-06-3 5-(4-bromophenyl)oxazole 
• 873-75-6 4-bromobenzenemethanol 
• 140-11-4 Benzyl acetate 

Relevant articles and documents

Application of poly(Vinylbenzyltrimethylammonium tribromide) resin as an efficient polymeric catalyst in the acetalization and diacetylation of benzaldehydes

The applications of a new supported tribromide reagent (poly(vinylbenzyltrimethylammonium tribromide) resin) were reported. This supported tribromide resin was used as a catalyst in the acetalization and diacetylation of benzaldehydes under mild conditions with high efficiency. The effects of solvents, and amount of the supported tribromide resin on the reactions were investigated. Under the optimal conditions, most of acetal and 1,1-diacetates of benzaldehydes were selectively obtained in excellent yields.

The studies on chemoselective promiscuous activity of hydrolases on acylals transformations

Chemoselective, mild and convenient protocol for the hydrolysis of the synthetically relevant acylals via promiscuous enzyme-catalyzed hydrolysis has been developed. It has been shown that promiscuous activity of the used hydrolases dominates their native activity related with carboxylic esters hydrolysis. The main advantage of the present methodology is that it can be conducted under neutral conditions at room temperature. Moreover, complete deprotection of acylals takes place within 10–20 min. Developed protocol can be used with compounds having a variety of hydrolytic labile groups since the cleavage is proceeded under neutral conditions and occurs exclusively on acylal moiety. Further this protocol was extended by the tandem Passerini multicomponent reaction leading to the α-acetoxy amides using acylals as the surrogates of the carbonyl components to P-MCR.

Chemoselective synthesis of 1,1-diacetates under solvent-free condition using efficient heterogeneous ecofriendly catalyst: P2O5/kaolin

An efficient and chemoselective method for the preparation of acylals from different aldehydes and acetic anhydride using.....kaolin supported catalyst (P2O5). under solvent-free conditions is described herein. The present protocol offers several advantages including use of inexpensive and non-toxic catalyst support i.e., natural kaolin. Preparation of the supported catalyst is easy, the process is simple in operation, maintaining solvent free conditions, with short reaction times, high yields and affording selective protection of aldehyde in presence of ketone.