55860-22-5

Basic information

• Product Name: 2-CHLORO-N-(2-METHOXYPHENYL)ACETAMIDE
• Synonyms: ART-CHEM-BB B015640;ASISCHEM U00018;CHEMBRDG-BB 3015640;2-CHLORO-N-(2-METHOXYPHENYL)ACETAMIDE;ACETAMIDE, 2-CHLORO-N-(2-METHOXYPHENYL)-;AKOS B015640;AKOS BBS-00003901;AKOS USSH-4110470
• CAS NO: 55860-22-5
• Molecular Formula: C₉H₁₀ClNO₂
• Molecular Weight: 199.63
• Mol File: 55860-22-5.mol
• Article Data: 50

Chemical Properties

• Boiling Point: 339 °C at 760 mmHg
• Flash Point: 158.8 °C
• Appearance: /
• Density: 1.264g/cm³
• Vapor Pressure: 2.66E-06mmHg at 25°C
• Refractive Index: 1.558
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-CHLORO-N-(2-METHOXYPHENYL)ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-N-(2-METHOXYPHENYL)ACETAMIDE(55860-22-5)
• EPA Substance Registry System: 2-CHLORO-N-(2-METHOXYPHENYL)ACETAMIDE(55860-22-5)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 55860-22-5(Hazardous Substances Data)

Usage

General Description

2-Chloro-N-(2-methoxyphenyl)acetamide is a chemical compound classified under the ACETAMIDE family. 2-CHLORO-N-(2-METHOXYPHENYL)ACETAMIDE is composed of an acetamide functional group where a chloro and a methoxyphenyl groups are attached. Specifically, it features a 2-chloroacetyl group bonded to an aryl amine in which the benzene ring carries a methoxy substituent at the 2-position. While its specific applications are not extensively documented, compounds in the acetamide class are generally known for their use in the pharmaceutical industry, often being incorporated into the creation of various drugs due to their diverse biological activities. Precise handling and caution should be adhered to when dealing with this chemical because its potential risks to human health and the environment are not fully established yet.

InChI:InChI=1/C14H13ClFNO/c1-9-7-11(14(18)8-15)10(2)17(9)13-6-4-3-5-12(13)16/h3-7H,8H2,1-2H3

Upstream product

• 90-04-0 2-methoxy-phenylamine 
• 79-04-9 chloroacetyl chloride 
• 255873-36-0 tert-butyl-N-{4-[allyl(dimethyl)silyl]-2-methoxyphenyl}carbamate 
• 59557-91-4 4-bromo-2-methoxyaniline 
• 262433-01-2 (4-bromo-2-methoxyphenyl)carbamic acid tert-butyl ester 

Downstream Products

• 38367-24-7 N-(2-methoxy-phenyl)-2-piperidin-1-yl-acetamide 
• 5466-88-6 3,4-dihydro-3-oxo-2H-1,4-benzoxazine 
• 332016-46-3 2-amino-N-(2-methoxyphenyl)ethanamide 
• 50824-49-2 N,N-diethyl-glycine o-anisidide 
• 101862-83-3 S--L-cystein 
• 108086-39-1 N-(2-Methoxy-phenyl)-2-(4-oxo-4H-quinazolin-3-yl)-acetamide 
• 134268-73-8 2-(2'-Hydroxy-biphenyl-2-yloxy)-N-(2-methoxy-phenyl)-acetamide 
• 93-26-5 2-methoxyacetanilide 
• 77775-76-9 N-glycoloyl-o-anisidine 
• 77775-77-0 N-ethoxyacetyl-o-anisidine 
• 79143-75-2 Diethyl-[(2-methoxy-phenylcarbamoyl)-methyl]-[(2,4,6-trimethyl-phenylcarbamoyl)-methyl]-ammonium; chloride 
• 17172-64-4 p-formylphenyl o-methoxyphenylcarbamoylmethyl ether 
• 139438-00-9 2-[5-(4-{[1-(1H-Indol-3-yl)-meth-(E)-ylidene]-amino}-phenyl)-4-phenyl-4H-[1,2,4]triazol-3-ylsulfanyl]-N-(2-methoxy-phenyl)-acetamide 
• 139438-07-6 2-[4-(4-Chloro-phenyl)-5-(4-{[1-(1H-indol-3-yl)-meth-(E)-ylidene]-amino}-phenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-N-(2-methoxy-phenyl)-acetamide 

Relevant articles and documents

Synthesis and Anti-inflammatory Activity of Some New 1,2,3-Benzotriazine Derivatives Using 2-(4-Oxo-6-phenylbenzo[d][1,2,3]triazin-3(4H)-yl)acetohydrazide as a Starting Material

In continuation to our search for new heterocyclic system-based anti-inflammatory activity, a series of novel 1,2,3-benzotriazine derivatives were synthesized. The pharmacological screening showed that many of these compounds have good anti-inflammatory activity. The structure assignments of the new synthesized compounds are based on spectroscopic data, and pharmacological properties are reported.

Synthesis of novel 1,2,3-triazoles bearing 2,4 thiazolidinediones conjugates and their biological evaluation

Searching for new active molecules against M. Bovis BCG and Mycobacterium tuberculosis (MTB) H37Ra, a focused of 1,2,3-triazoles-incorporated 2,4 thiazolidinedione conjugates have been efficiently prepared via a click chemistry approach cyclocondensation of 4-amino-N-(5-methylisoxazol-3-yl)benzenesulfonamide (4), aryl aldehyde (5a–l), and mercapto acetic acid (6) with good to promising yields. The newly synthesized compounds were tested against drug-sensitive MTB and BCG. In particular, compounds 8g, 8h, 8j and 8l are highly potent against both the strains with IC90 values in the range of 1.20–2.70 and 1.24–2.65?μg/mL, respectively. Based on the results from the antitubercular activity, SAR for the synthesized series has been developed. Most of the active compounds were non-cytotoxic against MCF-7, HCT 116 and A549 cell lines. Most active compounds were having a higher selectively index, which suggested that these compounds were highly potent.

Triazole sulfonamides derivatives and their use in agriculture

The invention provides a novel triazole sulfonamide derivative and application thereof in agriculture. , The invention relates to a triazole sulfonamides derivative as shown in a formula (I) and a preparation method thereof. I In formula (R)1 And R2 Are each independently hydrogen. C1 -6 Alkyl and the like, R3 Document C3 -8 Cycloalkyl, R4 -SO2 - NRa Rb , SO2 - C1 -6 Alkyl group, SO2 - C3 -8 Cycloalkyl, SO2 - C1 -3 Alkylene - C3 -8 Cycloalkyl, SO2 - Rc , C1 -3 Alkylene - C (＝ O) O-C1 -6 Alkyl or - C1 -3 Alkylene - C (＝ O) - NRd Re , Ra , Rb , Rc , Rd And Re Having the meaning of the invention. The compound, the composition containing the compound and/or the preparation provided by the invention has good bactericidal activity and can be used as a bactericide in agriculture.