56243-25-5 Usage
Description
1-Benzyl-4-cyano-4-phenylpiperidine hydrochloride is a piperidine derivative characterized as an off-white crystalline solid. It is a chemical compound with a unique structure that has potential applications in various fields due to its specific properties.
Uses
Used in Pharmaceutical Industry:
1-Benzyl-4-cyano-4-phenylpiperidine hydrochloride is used as a calcium channel blocker for the treatment of various cardiovascular conditions. Its chemical structure allows it to interact with calcium channels in the heart and blood vessels, leading to a reduction in blood pressure and improved cardiovascular function.
Used in Chemical Research:
As a piperidine derivative, 1-Benzyl-4-cyano-4-phenylpiperidine hydrochloride is also used in chemical research and development. Its unique properties make it a valuable compound for studying the effects of structural modifications on the activity and selectivity of various chemical and biological processes.
Used in Drug Synthesis:
1-Benzyl-4-cyano-4-phenylpiperidine hydrochloride can be utilized as an intermediate in the synthesis of other pharmaceuticals and active ingredients. Its off-white crystalline solid form makes it suitable for various chemical reactions and processes, contributing to the development of new drugs and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 56243-25-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,2,4 and 3 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 56243-25:
(7*5)+(6*6)+(5*2)+(4*4)+(3*3)+(2*2)+(1*5)=115
115 % 10 = 5
So 56243-25-5 is a valid CAS Registry Number.
InChI:InChI=1/C19H20N2/c20-16-19(18-9-5-2-6-10-18)11-13-21(14-12-19)15-17-7-3-1-4-8-17/h1-10H,11-15H2/p+1
56243-25-5Relevant articles and documents
A 4-substituted piperidine derivatives synthetic method
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Paragraph 0149-0152, (2020/02/07)
The invention relates to a synthesis method of 4-substituted piperidine derivatives. The synthesis method comprises the following steps: continuously reacting alpha-single substituted acetonitrile serving as a raw material with two-molecular ethylene oxide in the presence of a base I, thereby synthesizing compounds (2), wherein not one compound (2) is generated, and the compounds (2) are in tautomeric equilibrium with a compound (6); breaking the balance in the presence of a base II to generate an alcoxyl negative ion compound (3); reacting the compound (3) with R2SO2X or (R2SO2)2O to generate sulphonates (4); performing a cyclization reaction on the sulphonates (4) and primary amine to synthesize 4-substituted piperidine derivatives. Compared with a document reported method, the synthesis method has the advantages that the reaction steps are shortened and the synthetic efficiency is improved.
A convenient one-pot preparation of N-substituted 4-phenylpiperidines
Asano, Shigehiro,Ban, Hitoshi
, p. 183 - 188 (2008/09/20)
N-Substituted 4-phenylpiperidines were readily synthesized by one-pot cyclization of diols with amines via bis-triflate intermediates. The new synthesis under mild conditions gave various N-substituted 4-phenylpiperidines in moderate to good yields.
DIARYL PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS
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Page/Page column 44, (2008/06/13)
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