56741-33-4

Basic information

• Product Name: 5-Amino-2-fluorobenzioc acid
• Synonyms: RARECHEM AL BO 1979;BUTTPARK 19\01-52;3-AMINO-6-FLUOROBENZOIC ACID;5-AMINO-2-FLUOROBENZIOC ACID;5-AMINO-2-FLUOROBENZOIC ACID;5-Amino-2-fluorobenzoic acid 97%;5-Amino-2-fluorobenzoicacid97%;2-FLUORO-5-AMINOBENZOICACID
• CAS NO: 56741-33-4
• Molecular Formula: C₇H₆FNO₂
• Molecular Weight: 155.13
• Product Categories: Fluorin-contained Benzoic acid series;Fluorobenzene;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Benzoic acid;Fluorine series
• Mol File: 56741-33-4.mol
• Article Data: 6

Chemical Properties

• Melting Point: 190 °C
• Boiling Point: 351.3 °C at 760 mmHg
• Flash Point: 166.3 °C
• Appearance: /
• Density: 1.43 g/cm³
• Vapor Pressure: 1.54E-05mmHg at 25°C
• Refractive Index: 1.606
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 2.41±0.10(Predicted)
• CAS DataBase Reference: 5-Amino-2-fluorobenzioc acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Amino-2-fluorobenzioc acid(56741-33-4)
• EPA Substance Registry System: 5-Amino-2-fluorobenzioc acid(56741-33-4)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36-37
• Hazardous Substances Data: 56741-33-4(Hazardous Substances Data)

Usage

Chemical Properties

yellow powder

InChI:InChI=1/C7H6FNO2/c8-6-2-1-4(9)3-5(6)7(10)11/h1-3H,9H2,(H,10,11)

Upstream product

• 7304-32-7 2-fluoro-5-nitrobenzoic acid 
• 445-29-4 o-fluoro-benzoic acid 

Downstream Products

• 105459-28-7 di(3-carboxylato-4-fluorophenyl) disulphide 
• 220705-28-2 3-benzoxazol-2-yl-4-fluorophenylamine 
• 220705-29-3 3-benzothiazol-2-yl-4-fluorophenylamine 
• 635325-29-0 2-fluoro-5-[6-methyl-3-oxo-4-(3-trifluoromethyl-phenyl)-3,6-dihydro-1H-1,2,5,6,7-pentaaza-as-indacen-2-yl]-benzoic acid 
• 220705-30-6 diethyl 2-(((3-benzoxazol-2-yl-4-fluorophenyl)amino)methylene)propane-1,3-dioate 
• 220705-32-8 diethyl 2-(((3-benzothiazol-2-yl-4-fluorophenyl)amino)methylene)propane-1,3-dioate 
• 84832-00-8 (5-amino-2-fluoro-phenyl)-methanol 
• 84832-04-2 2-[(4-Fluoro-3-hydroxymethyl-phenylamino)-methylene]-malonic acid diethyl ester 
• 84832-06-4 diethyl 2-(3-acetoxymethyl-4-fluoroanilino)methylenemalonate 
• 632624-97-6 3-{2-[5-chloro-2-(benzyloxy)phenyl]-5-methyl-pyrrol-1-yl}-6-fluorobenzoic acid 
• 632624-28-3 3-{2-[5-chloro-2-(2,6-difluorobenzyloxy)phenyl]-5-methyl-pyrrol-1-yl}-6-fluorobenzoic acid 
• 632624-39-6 3-{2-[5-chloro-2-(2,3-difluorobenzyloxy)phenyl]-5-methyl-pyrrol-1-yl}-6-fluorobenzoic acid 
• 854195-41-8 3-[2-(5-bromo-2-isobutyloxy-phenyl)-pyrrol-1-yl]-6-fluoro-benzoic acid 
• 854194-95-9 3-[2-(5-chloro-2-isobutyloxy-phenyl)-5-methyl-pyrrol-1-yl]-6-fluoro benzoic acid sodium salt 

Relevant articles and documents

Mutasynthesis of fluorinated pactamycin analogues and their antimalarial activity

A mutasynthetic strategy has been used to generate fluorinated TM-025 and TM-026, two biosynthetically engineered pactamycin analogues produced by Streptomyces pactum ATCC 27456. The fluorinated compounds maintain excellent activity and selectivity toward chloroquine-sensitive and multidrug-resistant strains of malarial parasites as the parent compounds. The results also provide insights into the biosynthesis of 3-aminobenzoic acid in S. pactum.

Synthesis of 7-benzoxazol-2-yl and 7-Benzothiazol-2-yl-6-fluoro- quinolones

The fluoroquinolones, 7-benzoxazol-2-yl-1-ethyl-6-fluoro-1,4-dihydro-4- oxoquinoline-3-carboxylic acid and 7-benzothiazol-2-yl-1-ethyl-6-fluoro-1,4- dihydro-4-oxoquinoline-3-carboxylic acid, were synthesized. The compounds were obtained, by use of the Gou

Mass Spectrometric Fragmentation Reactions. XXXI-The Fragmentation Behaviour of o-Halobenzoic Acids Substituted in the 5-Position: A Novel Ortho Effect

A fragmentation sequence typical for o-halobenzoic acids carrying a heteroatom substituent in the 5-position is described.