57070-76-5

Basic information

• Product Name: 3-(2-Bromoethyl)thiophene
• Synonyms: 3-(2-Bromoethyl)thiophene;2-(Thiophene-3-yl)-1-bromoethane;Thiophene, 3-(2-bromoethyl)-
• CAS NO: 57070-76-5
• Molecular Formula: C₆H₇BrS
• Molecular Weight: 191
• Mol File: 57070-76-5.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 210℃
• Flash Point: 81℃
• Appearance: /
• Density: 1.529
• CAS DataBase Reference: 3-(2-Bromoethyl)thiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-Bromoethyl)thiophene(57070-76-5)
• EPA Substance Registry System: 3-(2-Bromoethyl)thiophene(57070-76-5)

Safety Data

• Hazardous Substances Data: 57070-76-5(Hazardous Substances Data)

Usage

General Description

3-(2-Bromoethyl)thiophene is an organic compound with the chemical formula C6H7BrS. This chemical is a derivative of thiophene, a five-membered aromatic ring containing four carbon atoms and one sulfur atom. The presence of a bromoethyl group on the thiophene ring gives 3-(2-Bromoethyl)thiophene unique properties and reactivity. Thiophenes are widely used in pharmaceuticals, agrochemicals, and organic electronic materials due to their aromatic and electron-rich nature. The bromoethyl group can also make this compound a valuable intermediate for the synthesis of various organic compounds and functional materials. Its interesting structure and potential applications make 3-(2-Bromoethyl)thiophene an important molecule in organic chemistry.

Upstream product

• 13781-67-4 3-(2-hydroxyethyl)thiophene 
• 1034-39-5 dibromotriphenylphosphorane 
• 14861-60-0 1-(thiophen-3-yl)ethan-1-ol 

Downstream Products

• 197094-83-0 3-Ethoxy-6-methyl-6-(2-thiophen-3-yl-ethyl)-cyclohex-2-enone 
• 197094-84-1 4-Methyl-4-(2-thiophen-3-yl-ethyl)-cyclohex-2-enone 
• 197094-86-3 5-Methyl-2-oxo-5-(2-thiophen-3-yl-ethyl)-cyclohex-3-enecarboxylic acid methyl ester 
• 1331849-49-0 3-[2-(3-thienyl)ethyl]aniline 
• 1331849-51-4 N,N'-di-[3-[2-(3-thienyl)ethyl]phenyl]perylene-3,4,9,10-bis(dicarboximide) 
• 852520-41-3 Methyl 3-isopropoxy-5-(2-(3-thienyl)ethoxy)benzoate 
• 852520-52-6 3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzoic acid 
• 852520-62-8 methyl 6-(3-isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinate 
• 1445236-19-0 tert-butylphenyl-2-(3-thiophenyl)ethylphosphine oxide 
• 1445236-17-8 (S)-t-butyl-2-(3'-thienyl)ethyl-phenyl phosphine oxide 
• 1505-47-1 4-(thien-3-yl)butyric acid 
• 1468-84-4 5,6-dihydro-4H-benzothiophen-7-one 

Relevant articles and documents

A new efficient route to 3-vinylthiophene

The synthesis of 3-vinylthiophene was efficiently achieved in two steps. 3-(2-bromoethyl)thiophene prepared from 3-(2- ethanol)thiophene was converted to the title compound (70% overall yield) using tetraglyme as a solvent and 1,8- diazabicyclo[5.4.0]undec-7-ene as a base.

Catalytic Asymmetric Disulfuration by a Chiral Bulky Three-Component Lewis Acid-Base

A three-component Lewis acid–base (Lewis trio) involving a bulky chiral primary amine, B(C6F5)3 and a bulky tertiary amine has been developed as an effective enamine catalyst for enantioselective disulfuration reactions. The bulky tertiary amine was found to activate a bulky primary–tertiary diamine–borane Lewis pair for enamine catalysis via frustrated interaction. The resulted chiral bulky Lewis trio (BLT) allows for the construction of chiral disulfides via direct disulfuration with β-ketocarbonyls or α-branched aldehydes in a practical and highly stereocontrolled manner.

NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF

The invention provides compounds for inhibiting glucosylceramidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds.

Small-molecule allosteric activation of human glucokinase in the absence of glucose

Synthetic allosteric activators of human glucokinase are receiving considerable attention as potential diabetes therapeutic agents. Although their mechanism of action is not fully understood, structural studies suggest that activator association requires