578703-92-1

Basic information

• Product Name: methyl 1-(4-fluorophenyl)-1H-1,2,3-triazole-4-carboxylate
• Synonyms: methyl 1-(4-fluorophenyl)-1H-1,2,3-triazole-4-carboxylate
• CAS NO: 578703-92-1
• Molecular Weight: 221.191
• Mol File: 578703-92-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 1-(4-fluorophenyl)-1H-1,2,3-triazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 1-(4-fluorophenyl)-1H-1,2,3-triazole-4-carboxylate(578703-92-1)
• EPA Substance Registry System: methyl 1-(4-fluorophenyl)-1H-1,2,3-triazole-4-carboxylate(578703-92-1)

Safety Data

• Hazardous Substances Data: 578703-92-1(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 578703-90-9 1-(4-fluorophenyl)-4,5-dihydro-1H-1,2,3-triazole-4-carbaldehyde 
• 3296-02-4 p-azidofluorobenzene 
• 922-67-8 propynoic acid methyl ester 
• 371-40-4 4-fluoroaniline 
• 34846-90-7 methyl 3-methoxyprop-2-enoate 

Downstream Products

• 310886-79-4 methyl 5-fluoro-1H-indole-3-carboxylate 
• 1185251-60-8 methyl N-(4-fluorophenyl)ketenimine-1-carboxylate 
• 1185251-67-5 C₁₀H₈FNO₂ 
• 1185251-55-1 2-methoxy-6-fluoro-4(1H)-quinolone 
• 578703-74-9 1-(4-fluorophenyl)-1H-1,2,3-triazole-4-carbohydrazide 

Relevant articles and documents

Direct access to 1,4-disubstituted 1,2,3-triazoles through organocatalytic 1,3-dipolar cycloaddition reaction of α,β-unsaturated esters with azides

DBU-catalyzed organocatalytic 1,3-dipolar cycloaddition reactions of α,β-unsaturated esters with azides have been developed. This strategy generates 1,4-disubstituted 1,2,3-triazoles in high yields with high regioselectivities. It is demonstrated that some of these products can be transformed into important pharmaceutical agents.

Arylazide cycloaddition to methyl propiolate: DFT-based quantitative prediction of regioselectivity

Several 1-(4-substituted)-phenyl-4- or 5-methoxycarbonyl-1,2,3-triazoles have been synthesized by 1,3-dipolar cycloaddition of the corresponding arylazides to methyl propiolate in carbon tetrachloride. The regioselectivity of these reactions cannot be rat