58556-55-1Relevant articles and documents
Chemoenzymatic synthesis and radical scavenging of sulfated hydroxytyrosol, tyrosol, and acetylated derivatives
Begines, Paloma,Biedermann, David,Valentova, Katerina,Petraskova, Lucie,Pelantova, Helena,Maya, Ines,Fernandez-Bola?os, Jose G.,Krěn, Vladimír
, p. 7281 - 7288 (2019)
Potential metabolites of bioactive compounds are important for their biological activities and as authentic standards for metabolic studies. The phenolic compounds contained in olive oil are an important part of the human diet, and therefore their potenti
Optimization of lipase-catalyzed synthesis of acetylated tyrosol by response surface methodology
Aissa, Imen,Bouaziz, Mohamed,Ghamgui, Hanen,Kamoun, Amel,Miled, Nabil,Sayadi, Sami,Gargouri, Youssef
, p. 10298 - 10305 (2007)
The ability of a noncommercial immobilized lipase from Staphylococcus xylosus (SXLi) to catalyze the transesterification of tyrosol and ethyl acetate was investigated. Response surface methodology was used to evaluate the effects of the tempera
3, 4-dihydroxyphenylethanol synthesis method
-
Paragraph 0033; 0034; 0038; 0039; 0043; 0044; 0048; 0049, (2019/04/02)
An embodiment of the invention discloses a 3, 4-dihydroxyphenylethanol synthesis method which includes the steps: taking a compound I as a raw material to prepare a compound II under the action of a catalyst for standby application; performing reaction on the compound II prepared in the first step and strong acid, and extracting and concentrating a reactant to prepare a compound III; dissolving the compound III in a solvent to perform reaction under the of a catalyst to prepare a compound IV; performing diazo-reaction and acidic hydrolysis on the compound IV to generate 3, 4-dihydroxyphenylethanol. According to the 3, 4-dihydroxyphenylethanol synthesis method, raw materials are moderate in cost, mass production is easily implemented, the purity of the 3, 4-dihydroxyphenylethanol is higherthan 99%, and overall yield can reach 78% or more. The synthesis method is simple in reaction condition, special requirements for devices are omitted, the method is easily implemented in industrial production, and organic solvents can be completely recycled and reused in the whole preparation process.
Lipase-mediated selective acetylation of primary alcohols in ethyl acetate
de Souza, Ernane C.,Romero-Ortega, Moises,Olivo, Horacio F.
supporting information, p. 287 - 290 (2017/12/29)
An environmental friendly process to selectively acetylate primary alcohols was demonstrated. The esterification process consists of treatment of a primary alcohol in the presence of immobilized C. antarctica lipase (Novozyme-435) in ethyl acetate at room temperature. Primary alcohols were acetylated in the presence of secondary alcohols and phenols.
