712223-57-9 Usage
Description
4-(2-Acetoxyethyl)phenol TrifluoroMethanesulfonate is an organic compound that serves as an important intermediate in the synthesis of various pharmaceuticals and chemical compounds.
Used in Pharmaceutical Industry:
4-(2-Acetoxyethyl)phenol TrifluoroMethanesulfonate is used as a reactant for the preparation of the immunosuppressive agent FTY720 (Fingolimod, F805000), which is a drug used to treat multiple sclerosis and other autoimmune diseases. It helps in modulating the immune response and reducing inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 712223-57-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,1,2,2,2 and 3 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 712223-57:
(8*7)+(7*1)+(6*2)+(5*2)+(4*2)+(3*3)+(2*5)+(1*7)=119
119 % 10 = 9
So 712223-57-9 is a valid CAS Registry Number.
712223-57-9Relevant articles and documents
Iron-catalyzed cross-coupling reactions. A scalable synthesis of the immunosuppressive agent FTY720
Seidel, Guenter,Laurich, Daniel,Fuerstner, Alois
, p. 3950 - 3952 (2007/10/03)
A chemo- and regioselective cross-coupling reaction of the functionalized aryl triflate 5 with octylmagnesium bromide catalyzed by cheap, nontoxic, and environmentally benign Fe(acac)3 sets the basis for a practical and scaleable synthesis of the octylbenzene derivative 6, which serves as a key building block for the preparation of FTY720 (1). This 2-amino-1,3-propanediol derivative shows highly promising immunosuppressive properties and is currently in human clinical phase III trials.
