58562-46-2 Usage
General Description
2-(carbamoylmethoxy)nitrobenzene is a chemical compound with a molecular formula C8H8N2O5. It is a nitrobenzene derivative with a carbamoylmethoxy functional group attached to the benzene ring. 2-(carbamoylmethoxy)nitrobenzene is used in the synthesis of various pharmaceuticals and organic compounds due to its ability to act as a building block in organic chemistry reactions. It is also used as a starting material for the production of other important chemical compounds. Additionally, it has potential applications in the field of medicinal chemistry and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 58562-46-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,5,6 and 2 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 58562-46:
(7*5)+(6*8)+(5*5)+(4*6)+(3*2)+(2*4)+(1*6)=152
152 % 10 = 2
So 58562-46-2 is a valid CAS Registry Number.
58562-46-2Relevant articles and documents
Pyrrolidinyl phenylurea derivatives as novel CCR3 antagonists
Nitta, Aiko,Iura, Yosuke,Inoue, Hideki,Imaoka, Takayuki,Takahashi, Toshiya,Sato, Ippei,Morihira, Koichiro,Kubota, Hirokazu,Morokata, Tatsuaki,Takeuchi, Makoto,Ohta, Mitsuaki,Tsukamoto, Shin-Ichi
, p. 6876 - 6881,6 (2020/09/02)
Optimization starting with our lead compound 1 (IC50 = 4.9 nM) led to the identification of pyrrolidinyl phenylurea derivatives. Further modification toward improvement of the bioavailability provided (R)-1-(1-((6-fluoronaphthalen-2-yl)methyl)pyrrolidin-3-yl)-3-(2-(2- hydroxyethoxy)phenyl)urea 32 (IC50 = 1.7 nM), a potent and orally active CCR3 antagonist.
