58909-56-1Relevant articles and documents
New indication of Qusuofen ceftriaxone sodium pharmaceutical preparation for treating pelvic inflammation
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Paragraph 0054; 0126-0129; 0135-0151, (2020/02/08)
The invention relates to the technical field of drug preparations and discloses a new indication of a Qusuofen ceftriaxone sodium pharmaceutical preparation for treating pelvic inflammation. The impurity content of ceftriaxone sodium provided by a specific production process is very low, the efficacy is significant, the quality of the preparation product is improved, the safety and effectiveness of the preparation product are guaranteed, and the pharmaceutical preparation has application in preparing a drug for treating the pelvic inflammation.
New indications of troxofine ceftriaxone sodium pharmaceutical preparation for treatment of infection of patients with immunodeficiency
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Paragraph 0118-0119; 0123-0124; 0144-0147, (2019/11/13)
The invention belongs to the technical field of drug preparation, and discloses new indications of a troxofine ceftriaxone sodium pharmaceutical preparation for treatment of infection of patients withimmunodeficiency. By improving a raw material synthesis process, ceftriaxone sodium with the high effective constituent content and the low impurity content is provided so as to solve the problems ofpoor stability and reducing of the antibacterial effect of a ceftriaxone sodium preparation due to impurities. The ceftriaxone sodium provided by the specific production process is very low in impurity content and significant in efficacy, the quality of a preparation product is improved advantageously, safety and effectiveness of the preparation product are ensured, and the preparation product has uses in the aspects of preparing drugs for treating infection of the patients with immunodeficiency.
A method of preparing ceftriazone sodium
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Paragraph 0030-0031, (2017/02/09)
The invention relates to a novel green low-cost method for synthesizing ceftriaxone sodium. Firstly, in the 7-ACT synthesis process, the dimethyl carbonate is used as the reaction solvent, and the boron trifluoride-dimethyl carbonate is used as the catalyst, thereby substituting the use of the high-cost high-toxicity acetonitrile; and secondly, in the ceftriaxone sodium synthesis process, the ethanol-water reaction system is adopted to obtain the high-yield high-quality ceftriaxone sodium.