59477-82-6 Usage
Description
1-(4-TERT-BUTYL-PHENYL)-2-CHLORO-PROPAN-1-ONE, also known as 4-tert-butyl-2-chloropropiophenone, is an organic compound belonging to the aromatic ketones class. It has the chemical formula C11H15ClO and is characterized by a phenyl ring with a tert-butyl group, a chlorine atom, and a propan-1-one functional group. This colorless liquid at room temperature is utilized as a key intermediate in the synthesis of various pharmaceuticals and organic compounds. Due to its hazardous nature, it requires careful handling to prevent harm from ingestion or inhalation.
Uses
Used in Pharmaceutical Industry:
1-(4-TERT-BUTYL-PHENYL)-2-CHLORO-PROPAN-1-ONE is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new medications and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(4-TERT-BUTYL-PHENYL)-2-CHLORO-PROPAN-1-ONE is used as an intermediate in the production of insecticides and other chemicals that help protect crops from pests and enhance agricultural productivity.
Check Digit Verification of cas no
The CAS Registry Mumber 59477-82-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,4,7 and 7 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 59477-82:
(7*5)+(6*9)+(5*4)+(4*7)+(3*7)+(2*8)+(1*2)=176
176 % 10 = 6
So 59477-82-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H17ClO/c1-9(14)12(15)10-5-7-11(8-6-10)13(2,3)4/h5-9H,1-4H3/t9-/m1/s1
59477-82-6Relevant articles and documents
Photochemical Rearrangement of α-Chloro-Propiophenones to α-Arylpropanoic Acids: Studies on Chirality Transfer and Synthesis of (S)-(+)-Ibuprofen and (S)-(+)-Ketoprofen
Sonawane, Harikisan,Bellur, Nanjundiah S.,Kulkarni, Dilip G.,Ayyangar, Nagaraj R.
, p. 1243 - 1260 (2007/10/02)
A new single-step efficient photochemical approach for α-arylpropanoic acids (4) from α-chloro-propiophenones (5) is described.It involves carbonyl triplet excited state directed 1,2-aryl migration of the aryl group which has been found to be highly dependent upon the nature of the aryl substituent.The mode of the rearrangement is probed by the study of the photobehaviour of a set of optically active α-chloro-propiophenones.The results suggest that the nature of the carbonyl triplets (n, ?*/ ?, ?*) plays an important role in the chirality transfer.This method finds application in the synthesis of optically active ibuprofen (4e) and ketoprofen (26), though in moderate optical yields.
P-tert-butyl-diphenylalkane insecticides
-
, (2008/06/13)
1,1-Diphenylalkanes having a p-tert-butyl and a p'-alkoxy group substituted thereon are a novel class of compounds having a broad range of insecticidal activity.
