71209-71-7

Basic information

• Product Name: 4'-TERT-BUTYLPROPIOPHENONE
• Synonyms: BUTTPARK 97\11-96;AKOS B000310;4-TERT-BUTYLPROPIONYLBENZENE;4'-TERT-BUTYLPROPIOPHENONE;1-[4-(TERT-BUTYL)PHENYL]PROPAN-1-ONE;Butylpropiophenone;P-TERT-BUTYL PROPIOPHENONE;4''-TERT-BUTYLPROPIOPHENONE 95+%
• CAS NO: 71209-71-7
• Molecular Formula: C₁₃H₁₈O
• Molecular Weight: 190.28
• EINECS: 275-265-0
• Mol File: 71209-71-7.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 162 °C / 5mmHg
• Flash Point: 112.3 °C
• Appearance: /
• Density: 0.96
• Refractive Index: 1.5160-1.5190
• CAS DataBase Reference: 4'-TERT-BUTYLPROPIOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-TERT-BUTYLPROPIOPHENONE(71209-71-7)
• EPA Substance Registry System: 4'-TERT-BUTYLPROPIOPHENONE(71209-71-7)

Safety Data

• Hazard Codes: Xi
• RIDADR: 1993
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 71209-71-7(Hazardous Substances Data)

Usage

General Description

4'-Tert-Butylpropiophenone is a chemical compound often used in the synthesis of other compounds, particularly in pharmaceuticals. It is an organic substance, appearing as a light yellow liquid, and is considered safe when used as directed. However, this chemical is not commonly found in mainstream commercial products due to its highly specialized applications. The compound's structure consists of a propiophenone backbone with a tert-butyl functional group attached, and it's typically synthesized in a laboratory setting. As with many chemicals, proper safety measures should be taken while handling 4’-Tert-Butylpropiophenone to avoid any potential health complications.

Upstream product

• 253185-03-4 tert-butylbenzene 
• 79-03-8 propionyl chloride 
• 59477-82-6 α-chloro-4-t-butylpropiophenone 
• 127896-25-7 1-(4-tert-butylphenyl)propan-1-ol 
• 1746-23-2 4-tert-Butylstyrene 
• 97-94-9 triethyl borane 
• 26459-51-8 4-tert-butylbenzoic acid phenyl ester 
• 939-97-9 4-tert-Butylbenzaldehyde 
• 557-20-0 diethylzinc 
• 3972-65-4 1-bromo-4-tert-butylbenzene 
• 74-96-4 ethyl bromide 
• 64-18-6 formic acid 
• 35779-04-5 1-tert-butyl-4-iodobenzene 
• 925-90-6 ethylmagnesium bromide 

Downstream Products

• 87839-85-8 3-(4-tert-butyl-phenyl)-2-methyl-pentan-3-ol 
• 87839-86-9 3-(4-tert-Butylphenyl)-5-methyl-3-hexanol 
• 127896-25-7 1-(4-tert-butylphenyl)propan-1-ol 
• 60561-82-2 1-(4-(tert-butyl)phenyl)-2-methylpropan-1-one 
• 79342-02-2 1-tert-Butyl-4-((E)-1-methoxy-propenyl)-benzene 
• 154320-48-6 (+/-)-2-(4-tert-butylphenyl)propionic acid methyl ester 
• 40150-91-2 2-(4-tert-butylphenyl)propionic acid 
• 87840-01-5 4-(4-tert-Butylphenyl)-2-methylhexan 
• 77565-38-9 2-bromo-1-(4-tert-butylphenyl)propan-1-one 
• 1186309-72-7 5-[1-(4-tert-butylphenyl)propylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 1097726-60-7 C₂₆H₃₂N₄O₃ 
• 1202873-68-4 3-(4-tert-butylphenyl)-1,4-dimethyl-1H-pyrazol-5-ol 
• 1225498-64-5 C₁₅H₂₀O₃ 

Relevant articles and documents

A Mild Heteroatom (O -, N -, and S -) Methylation Protocol Using Trimethyl Phosphate (TMP)-Ca(OH) 2Combination

A mild heteroatom methylation protocol using trimethyl phosphate (TMP)-Ca(OH)2combination has been developed, which proceeds in DMF, or water, or under neat conditions, at 80 °C or at room temperature. A series of O-, N-, and S-nucleophiles, including phenols, sulfonamides, N-heterocycles, such as 9H-carbazole, indole derivatives, and 1,8-naphthalimide, and aryl/alkyl thiols, are suitable substrates for this protocol. The high efficiency, operational simplicity, scalability, cost-efficiency, and environmentally friendly nature of this protocol make it an attractive alternative to the conventional base-promoted heteroatom methylation procedures.

Cobalt-Catalyzed Migrational Isomerization of Styrenes

An efficient cobalt-catalyzed migrational isomerization of styrenes was developed using the thiazoline iminopyridine (TIP) ligand. This reaction is operationally simple and atom-economical using readily available starting materials to access trisubstituted alkenes. Even when using a 0.1 mol % catalyst loading, the reaction could be conducted in neat and completed in 1 h with excellent conversion and high E stereoselectivity.

Photoinduced C—C Bond Cleavage and Oxidation of Cycloketoxime Esters

A novel structural reorganization of cycloketoxime esters beyond the traditional Beckmann rearrangement process has been established to build cyano-containing ketones in the presence of photocatalyst. This novel transformation is remarkable with selective C—C bond cleavage and an oxidation process enabled by DMSO used as the solvent, oxidant, and oxygen source avoiding acid, base and toxic cyanide salts as the cyano source. Further applications in late-stage modification of complex and chiral molecules have also been reported.