6056-23-1

Basic information

• Product Name: ethyl (2-methoxyphenyl)acetate
• Synonyms: ethyl (2-methoxyphenyl)acetate;ethyl-2-(2-methoxyphenyl)acetate;(2-Methoxyphenyl)acetic acid ethyl ester;2-Methoxybenzeneacetic acid ethyl ester;Einecs 227-982-5
• CAS NO: 6056-23-1
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.22706
• EINECS: 227-982-5
• Mol File: 6056-23-1.mol
• Article Data: 20

Chemical Properties

• Melting Point: 123-124 °C
• Boiling Point: 261.1°C at 760 mmHg
• Flash Point: 103.5°C
• Appearance: /
• Density: 1.062g/cm³
• Vapor Pressure: 0.0118mmHg at 25°C
• Refractive Index: 1.497
• CAS DataBase Reference: ethyl (2-methoxyphenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (2-methoxyphenyl)acetate(6056-23-1)
• EPA Substance Registry System: ethyl (2-methoxyphenyl)acetate(6056-23-1)

Safety Data

• Hazardous Substances Data: 6056-23-1(Hazardous Substances Data)

Usage

Description

Ethyl (2-methoxyphenyl)acetate is a colorless liquid chemical compound with a sweet, floral aroma reminiscent of lily of the valley. It is commonly used in the fragrance and flavor industry and is found naturally in fruits such as pineapple and grapes. This versatile compound is considered safe for use in products intended for human consumption and has low volatility, making it a popular choice for long-lasting fragrance formulations.

Uses

Used in Fragrance Industry:
Ethyl (2-methoxyphenyl)acetate is used as a scent enhancer in perfumes for its sweet, floral aroma reminiscent of lily of the valley. Its low volatility contributes to the long-lasting nature of fragrance formulations.
Used in Flavor Industry:
Ethyl (2-methoxyphenyl)acetate is used as a flavoring agent in food and beverages, adding a sweet, floral taste that enhances the overall flavor profile of these products.
Used in Natural Flavors:
Ethyl (2-methoxyphenyl)acetate is used in the development of natural flavors, as it is found naturally in fruits such as pineapple and grapes. This makes it a desirable ingredient for products seeking a natural and authentic taste.

InChI:InChI=1/C11H14O3/c1-3-14-11(12)8-9-6-4-5-7-10(9)13-2/h4-7H,3,8H2,1-2H3

Upstream product

• 64-17-5 ethanol 
• 93-25-4 2-methoxyphenylacetic acid 
• 7035-03-2 2-methoxy-benzeneacetonitrile 
• 578-57-4 2-bromoanisole 
• 681-94-7 ethyl 2-(tributylstannyl)acetate 
• 150-46-9 triethyl borate 
• 7035-02-1 o-Methoxybenzyl chloride 
• 5720-06-9 2-Methoxyphenylboronic acid 
• 105-36-2 ethyl bromoacetate 
• 90843-72-4 3-(2-methoxy-phenyl)-2-thioxo-propionic acid 
• 28033-63-8 2-(2-methoxyphenyl)acetyl chloride 
• 766-51-8 2-Chloroanisole 
• 6148-64-7 ethyl potassium malonate 
• 612-16-8 (2-methoxyphenyl)methanol 

Downstream Products

• 78024-74-5 diethyl 2-(2-methoxyphenyl)malonate 
• 153687-09-3 4-hydroxy-3-(o-methoxyphenyl)-1,8-naphthyridin-2(1H)-one 
• 119540-42-0 2-(2-Methoxy-phenyl)-3-[1-(4-methoxy-phenyl)-5-p-tolyl-1H-pyrazol-3-yl]-propionic acid ethyl ester 
• 2001-49-2 trans-1,2,3,4,4a,5,6,8a-octahydronaphthalene 
• 1123-79-1 (+/-)-cis-1,2,3,4,4a,5,6,8a-octahydro-naphthalene 
• 111088-27-8 Bis-(3-ethoxycarbonylmethyl-4-methoxy-phenyl)-iodonium; iodide 
• 81616-76-4 2-(2-methoxyphenyl)propenoic acid ethyl ester 
• 185347-49-3 α-(o-anisyl)-γ-butyrolactone 
• 400602-58-6 2-(2-methoxy-phenyl)-3-oxo-succinic acid diethyl ester 
• 124028-81-5 6-chloro-4-hydroxy-3-(2-methoxyphenyl)-2(1H)-quinolinone 
• 75256-37-0 4-hydroxy-3-(o-methoxyphenyl)-1,2-dihydroquinolin-2-one 
• 400602-59-7 4,6-dihydroxy-3-(2-methoxy-phenyl)-1H-quinolin-2-one 
• 153687-11-7 2,4-dichloro-3-(o-methoxyphenyl)-1,8-naphthyridine 
• 111087-95-7 (S)-2-Amino-3-[4-(3-carboxymethyl-4-hydroxy-phenoxy)-3,5-diiodo-phenyl]-propionic acid 

Relevant articles and documents

Coupling of Reformatsky Reagents with Aryl Chlorides Enabled by Ylide-Functionalized Phosphine Ligands

The coupling of aryl chlorides with Reformatsky reagents is a desirable strategy for the construction of α-aryl esters but has so far been substantially limited in the substrate scope due to many challenges posed by various possible side reactions. This limitation has now been overcome by the tailoring of ylide-functionalized phosphines to fit the requirements of Negishi couplings. Record-setting activities were achieved in palladium-catalyzed arylations of organozinc reagents with aryl electrophiles using a cyclohexyl-YPhos ligand bearing an ortho-tolyl-substituent in the backbone. This highly electron-rich, bulky ligand enables the use of aryl chlorides in room temperature couplings of Reformatsky reagents. The reaction scope covers diversely functionalized arylacetic and arylpropionic acid derivatives. Aryl bromides and chlorides can be converted selectively over triflate electrophiles, which permits consecutive coupling strategies.

Synthetic method of benzofuranone

The invention provides a synthetic method of benzofuranone. According to the method, o-cresol which is relatively easy to obtain is used as an initial raw material, and the target product benzofuranone is prepared through four-step reaction; and the whole preparation process is mild in condition, high in yield, easy to operate, small in environmental pollution and suitable for large-scale industrial production.

ARTIFICIAL METALLOENZYMES CONTAINING NOBLE METAL-PORPHYRINS

The present invention is drawn to artificial metalloenzymes for use in cyclopropanation reactions, amination and C—H insertion.