61871-80-5

Basic information

• Product Name: Ethanone, 1-(2-amino-5-methylphenyl)-2-chloro- (9CI)
• Synonyms: Ethanone, 1-(2-amino-5-methylphenyl)-2-chloro- (9CI)
• CAS NO: 61871-80-5
• Molecular Formula: C₉H₁₀ClNO
• Molecular Weight: 183.6348
• Product Categories: ACETYLHALIDE
• Mol File: 61871-80-5.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethanone, 1-(2-amino-5-methylphenyl)-2-chloro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(2-amino-5-methylphenyl)-2-chloro- (9CI)(61871-80-5)
• EPA Substance Registry System: Ethanone, 1-(2-amino-5-methylphenyl)-2-chloro- (9CI)(61871-80-5)

Safety Data

• Hazardous Substances Data: 61871-80-5(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(2-amino-5-methylphenyl)-2-chloro- (9CI) is a chemical compound with the molecular formula C9H10ClNO. It is a chlorinated derivative of acetophenone with an amino group attached to the benzene ring. This chemical compound is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various medications. It has the potential to exhibit biological activity and may have applications in drug discovery and development. The presence of the amino and chloro groups in its structure makes it a valuable building block for the synthesis of more complex organic molecules with potential pharmacological properties. Further research and testing may be needed to fully understand the properties and potential uses of Ethanone, 1-(2-amino-5-methylphenyl)-2-chloro- (9CI).

Upstream product

• 106-49-0 p-toluidine 
• 107-14-2 chloroacetonitrile 

Downstream Products

• 614-96-0 5-methyl-1H-indole 
• 109532-28-7 2-(Acetylamino)-α-chlor-5-methylacetophenon 
• 164788-95-8 diethyl acetamido-(2-amino-5-methylphenacyl)-malonate 
• 92554-52-4 5-methyl-3-(phenylsulfanyl)indole 

Relevant articles and documents

Synergistic Cooperative Effect of Sodium borohydride-Iodine Towards Cascade C?N and C?S/Se Bond Formation: One-pot Regioselective Synthesis of 3-Sulfenyl/selenyl Indoles and Mechanistic Insight

In this work, a new strategy to synthesize 3-sulfenyl/selenyl indole is reported wherein LC?MS reveals a novel insight into synergistic cooperative effect of NaBH4-I2 which allows cascade C?N and C?S/C?Se bond formations via reduction-nucleophilic cyclization-chalcogenylation, three steps in one-pot, towards regioselective synthesis of diverse 3-chalcogenyl indoles including 5-bromo-3-[(3,4,5-trimethoxyphenyl)thio]-1H-indole, a known lead anticancer compound, directly from 2-amino-phenacylchlorides and thiophenols or disulfides/diselenides in aqueous dioxane under transition-metal-free condition. (Figure presented.).

Synthesis and bioevaluation of 22-hydroxyacuminatine analogs

A series of 22-hydroxyacuminatine analogs was prepared by using different Friedlaender condensations. Several of the new compounds were tested for antiproliferative activity on cancer cell lines and for topoisomerase I inhibitory activity.

Substituted kynurenines and process for their preparation

The present invention relates to the use in the treatment of cognitive disorders associated with the aging processes of the brain and perinatal brain disorders of compounds which act as inhibitors of the enzyme kynurenine aminotransferase (KAT). The prese