62101-46-6

Basic information

• Product Name: 2-chloro-3-[(4-methylphenyl)amino]naphthalene-1,4-dione
• Synonyms: 1,4-Naphthalenedione, 2-chloro-3-((4-methylphenyl)amino)-; 1,4-Naphthalenedione, 2-chloro-3-[(4-methylphenyl)amino]-; 2-chloro-3-(4-toluidino)-1,4-dihydronaphthalene-1,4-dione; 2-Chloro-3-[(4-methylphenyl)amino]-1,4-naphthoquinone
• CAS NO: 62101-46-6
• Molecular Formula: C₁₇H₁₂ClNO₂
• Molecular Weight: 297.7357
• Mol File: 62101-46-6.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 420.5°C at 760 mmHg
• Flash Point: 208.1°C
• Density: 1.36g/cm³
• Vapor Pressure: 2.81E-07mmHg at 25°C
• Refractive Index: 1.659
• CAS DataBase Reference: 2-chloro-3-[(4-methylphenyl)amino]naphthalene-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-3-[(4-methylphenyl)amino]naphthalene-1,4-dione(62101-46-6)
• EPA Substance Registry System: 2-chloro-3-[(4-methylphenyl)amino]naphthalene-1,4-dione(62101-46-6)

Safety Data

• Hazardous Substances Data: 62101-46-6(Hazardous Substances Data)

Upstream product

• 117-80-6 2,3-Dichloro-1,4-naphthoquinone 
• 64-17-5 ethanol 
• 106-49-0 p-toluidine 
• 64-19-7 acetic acid 
• 110-86-1 pyridine 
• 17087-90-0 N-(4-dimethylaminobenzylidene)-p-toluidine 
• 2272-45-9 benzal-p-toluidine 
• 24764-92-9 1,4-bis(p-tolyl)-1,4-diaza-1,3-butadiene 
• 57182-49-7 2-(p-toluidino)-1,4-naphthoquinone 
• 605-69-6 1-hydroxy-2,4-dinitronaphthalene 
• 108-44-1 1-amino-3-methylbenzene 

Downstream Products

• 104307-24-6 2-(p-methylphenylimino)-3,3-dichloro-2,3-dihydro-1,4-naphthoquinone 
• 150127-45-0 TW-85 
• 1569968-19-9 2-chloro-3-(2,6-dibromo-4-methylphenylamino)naphthalene-1,4-dione 
• 1427070-22-1 2-(4-methyl-2-nitrophenylamino)-3-chloronaphthalene-1,4-dione 
• 95291-76-2 2-(piperidin-1-yl)-3-[(4-methylphenyl)amino]naphthalene-1,4-dione 

Relevant articles and documents

Synthesis and in vitro evaluation of novel liver X receptor agonists based on naphthoquinone derivatives

We aimed to synthesize novel liver X receptor (LXR) agonists with potent agonist activity and subtype selectivity. Our synthetic scheme started with naphthoquinone derivatives, such as menadione and 2,3-dichloro-1,4-naphthoquinone. We introduced different

Synthesis and Antimicrobial Evaluation of 1,4-Naphthoquinone Derivatives as Potential Antibacterial Agents

1,4-Naphthoquinones are an important class of compounds present in a number of natural products. In this study, a new series of 1,4-naphthoquinone derivatives were synthesized. All the synthesized compounds were tested for in vitro antimicrobial activity.

Charge transfer facilitated direct electrophilic substitution in phenylaminonaphthoquinones: Experimental, theoretical and electrochemical studies

A simple and effective synthetic protocol to introduce electron withdrawing substitutents (Br and NO2) in the phenyl ring of 2-(p-R-phenylamino)-3-chloro-1,4-naphthoquinones (where R = H, Me, OMe, F and Cl; 1a-e) has been demonstrated using the