6279-51-2

Basic information

• Product Name: 4-AMINO-6-METHOXYQUINOLINE
• Synonyms: 4-AMINO-6-METHOXYQUINOLINE;6-Methoxyquinolin-4-amine
• CAS NO: 6279-51-2
• Molecular Formula: C₁₀H₁₀N₂O
• Molecular Weight: 174.2
• Mol File: 6279-51-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 369.6 °C at 760 mmHg
• Flash Point: 177.4 °C
• Appearance: /
• Density: 1.217 g/cm³
• Vapor Pressure: 1.17E-05mmHg at 25°C
• Refractive Index: 1.664
• CAS DataBase Reference: 4-AMINO-6-METHOXYQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-6-METHOXYQUINOLINE(6279-51-2)
• EPA Substance Registry System: 4-AMINO-6-METHOXYQUINOLINE(6279-51-2)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 6279-51-2(Hazardous Substances Data)

Usage

General Description

4-Amino-6-methoxyquinoline is a chemical compound with the molecular formula C10H9N3O. It is an organic compound with a quinoline backbone substituted with an amino group at the 4-position and a methoxy group at the 6-position. 4-AMINO-6-METHOXYQUINOLINE is commonly used in the synthesis of pharmaceuticals and has shown potential as an antimalarial agent. It exhibits antiproliferative and cytotoxic effects on cancer cells, making it a promising candidate for cancer treatment. Additionally, 4-amino-6-methoxyquinoline has been studied for its antimicrobial activity and as a potential dye in the textile industry. Its versatile properties and potential applications make it a valuable chemical compound in various scientific and industrial fields.

InChI:InChI=1/C10H10N2O/c1-13-7-2-3-10-8(6-7)9(11)4-5-12-10/h2-6H,1H3,(H2,11,12)

Upstream product

• 186581-53-3 diazomethane 
• 871876-07-2 4-amino-quinolin-6-ol 
• 5263-87-6 6-methoxy quinoline 
• 4295-04-9 4-chloro-6-methoxyquinoline 
• 4363-96-6 NCI 27532 
• 856098-77-6 (6-methoxy-[4]quinolyl)-carbamic acid ethyl ester 
• 917471-40-0 6-methoxy-4-nitro-quinoline 
• 6563-13-9 6-methoxyquinoline N-oxide 
• 25015-35-4 6-Methoxy-4-nitro-chinolin-1-oxid 
• 40107-09-3 4,5-Diamino-chinolin 
• 86-68-0 6-methoxyquinoline-4-carboxylic acid 
• 29620-63-1 6-methoxy-quinoline-4-carboxylic acid hydrazide 
• 5345-57-3 6-methoxyquinoline-4-carboxylic acid ethyl ester 
• 394223-55-3 C₁₅H₁₈N₂O₃ 

Downstream Products

• 5427-52-1 (4-diethylamino-benzylidene)-(6-methoxy-[4]quinolyl)-amine 
• 42881-66-3 4-bromo-6-methoxyquinoline 
• 876492-00-1 4-iodo-6-methoxyquinoline 
• 3517-61-1 4,6-dihydroxyquinoline 
• 877457-53-9 [3-(6-methoxy-quinolin-4-ylcarbamoyl)-cyclohexylmethyl]-carbamic acid tert-butyl ester 
• 611-35-8 4-chloroquinoline 
• 1392422-15-9 N-((4-chlorophenyl)(4-(1-tert-butoxycarbonylpiperazin-4-ylmethyl)phenyl)methyl)-6-methoxy-4-aminoquinoline 

Relevant articles and documents

PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES

The invention generally relates to methods of making substituted arenes via direct C-H amination. More specifically, methods of making para- and ortho-substituted arenes via direct C-H amination are disclosed. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

An unusual de-nitro reduction of 2-substituted-4-nitroquinolines

The treatment of a variety of 2-substituted-4-nitroquinolines with Sn in the presence of concentrated hydrochloric acid in ethanol at 70 °C for 2-4 h afforded unusual de-nitro products 2-substituted-quinolines in good yields.

Aminopiperidine quinolines and their azaisosteric analogues with antibacterical activity

Aminopiperidine derivatives of formula (I) and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.