63762-91-4

Basic information

• Product Name: Ethanone, 2-[(3-methoxyphenyl)thio]-1-phenyl-
• CAS NO: 63762-91-4
• Molecular Formula: C15H14O2S
• Molecular Weight: 258.341
• Mol File: 63762-91-4.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-[(3-methoxyphenyl)thio]-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-[(3-methoxyphenyl)thio]-1-phenyl-(63762-91-4)
• EPA Substance Registry System: Ethanone, 2-[(3-methoxyphenyl)thio]-1-phenyl-(63762-91-4)

Safety Data

• Hazardous Substances Data: 63762-91-4(Hazardous Substances Data)

Upstream product

• 536-74-3 phenylacetylene 
• 16717-64-9 1-azidostyrene 
• 15570-12-4 3-methoxybenzenethiol 
• 98-88-4 benzoyl chloride 
• 20718-17-6 2-(dimethyl(oxo)-λ⁶-sulfaneylidene)-1-phenylethan-1-one 
• 1021-45-0 phosphoric acid diethyl ester-(1-phenyl-vinyl ester) 
• 59014-89-0 bis(3-methoxyphenyl)disulfide 
• 16222-10-9 1-phenyl-2-(phenylthio)ethanone 
• 2388-74-1 1-methoxy-3-methylsulfanyl-benzene 
• 70-11-1 α-bromoacetophenone 
• 532-27-4 1-chloroacetophenone 

Downstream Products

• 92014-01-2 2-phenyl-6-methoxybenzothiophene 

Relevant articles and documents

An aryl thiol-vinyl azide coupling reaction and a thiol-vinyl azide coupling/cyclization cascade: efficient synthesis of β-ketosulfides and arene-fused 5-methylene-2-pyrrolidinone derivatives

The addition reaction of thiol to vinyl azide has been extensively studied. Variously substituted aryl thiols are all viable for this coupling process. The scope of the other partner is successfully expanded from α-aryl vinyl azide to α-alkyl vinyl azide.

Iridium-Catalyzed Carbenoid Insertion of Sulfoxonium Ylides for Synthesis of Quinoxalines and β-Keto Thioethers in Water

Sulfoxonium ylides as safe carbene precursors are described for iridium-catalyzed carbene insertions and annulation, providing a facile and green approach to access a variety of quinoxaline derivatives in water. This water-mediated method also allows the preparation of β-keto thioethers under mild condition.

MODULATORS OF ESTROGEN RECEPTOR PROTEOLYSIS AND ASSOCIATED METHODS OF USE

The present disclosure relates to bifunctional compounds, which find utility as modulators of estrogen receptor (target protein). In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a cereblon, Von Hippel-Lindau ligase-binding moiety, Inhibitors of Apotosis Proteins, or mouse double-minute homolog 2 ligand, which binds to the respective E3 ubiquitin ligase, and on the other end a moiety which binds the target protein, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of target protein. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aggregation or accumulation of the target protein are treated or prevented with compounds and compositions of the present disclosure.