65136-51-8Relevant articles and documents
Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment
Montanari, Serena,Mahmoud, Ali Mokhtar,Pruccoli, Letizia,Rabbito, Alessandro,Naldi, Marina,Petralla, Sabrina,Moraleda, Ignacio,Bartolini, Manuela,Monti, Barbara,Iriepa, Isabel,Belluti, Federica,Gobbi, Silvia,Di Marzo, Vincenzo,Bisi, Alessandra,Tarozzi, Andrea,Ligresti, Alessia,Rampa, Angela
, p. 243 - 258 (2019/06/14)
To address the multifactorial nature of Alzheimer's Disease (AD), a multi-target-directed ligand approach was herein developed. As a follow-up of our previous studies, a small library of newly designed 2-arylbenzofuran derivatives was evaluated towards ch
MONOCYCLIC PYRIDINE DERIVATIVE
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Paragraph 0372; 0373; 0374, (2014/09/03)
The present invention provides a novel compound having FGFR inhibitory activity or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing the same. Specifically, the present invention provides a compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof: wherein n represents 0 to 2; A represents an arylene group or a heteroarylene group; G represents a single bond, an oxygen atom or —CH2—; E represents a nitrogen-containing non-aromatic heterocycle; R1 represents an alkoxy group or the like; R2 represents a hydrogen atom or the like; and R3 represents a hydrogen atom, an alkyl group, an alkoxy group or the like, with the proviso that when E represents an azetidine ring and R2 or R3 is present on a nitrogen atom on the azetidine ring, the R2 or R3 does not represent a hydrogen atom.
Benzothiophenes and related compounds as estrogen agonists
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Page/Page column 42, (2010/02/07)
The invention is a compound of Formula (I): wherein R is —OH, R1is —OH, R2is —H, n is 2 or 3 and X is sulfur, or a pharmaceutically acceptable salt of a compound having Formula (1), or a pharmaceutical composition comprising a compou