66536-76-3Relevant articles and documents
Chemoenzymatic synthesis of β-hydroxyl-sulfoxides by a two-step reaction of enzymatic reduction using Pseudomonas monteilii species and sulfoxidation with chiral titanium complexe
Cui, Baodong,Yang, Min,Shan, Jing,Qin, Lei,Liu, Ziyan,Wan, Nanwei,Han, Wenyong,Chen, Yongzheng
, p. 5200 - 5206 (2017/07/28)
A two-step enantioselective synthetic strategy for the preparation of β-hydroxyl-sulfoxides has been described. With the enzymatic reduction of β-ketosulfides using Pseudomonas monteilii ZMU-T04 followed by the asymmetric sulfoxidation with Ti(OiPr)4/(S)-BINOL complexe, a wide range of corresponding β-hydroxyl-sulfoxide derivatives were smoothly obtained with excellent stereoselectivities (up to 99:1 dr and >99% ee). A plausible chelate structure of titanium complexe in the asymmetric sulfoxidation of β-hydroxyl-sulfides was also proposed on the basis of control experiments.
Formation of single diastereomers of β-hydroxy-sulfoxides by biotransformation of β-ketosulfides using Helminthosporium species NRRL 4671
Holland, Herbert L.,Ihasz, Nancy,Lounsbery, Brendan J.
, p. 640 - 642 (2007/10/03)
Single biotransformations of 1-(phenylthio)-2-propanone and 1-(p-methoxyphenylthio)-2-propanone by the fungus Helminthosporium species NRRL 4671 resulted in both sulfur oxidation to the sulfoxide and carbonyl reduction to the alcohol. The corresponding (SS,SC)-1-sulfinyl-2-propanols were obtained as single diastereomers following simple crystallization.
Effect of Intramolecular Chelation on Configurational Interconversion of Sulphur-stabilized Carbanions
Tanikaga, Rikuhei,Hamamura, Kazumasa,Hosoya, Ken,Kaji, Aritsune
, p. 817 - 818 (2007/10/02)
Sulphur-stabilized carbanions R1R2-SO undergo configurational interconversion, which is affected by intramolecular chelation and the bulk of R.
