6880-04-2

Basic information

• Product Name: 4-Methoxy-3-methylbenzoic acid
• Synonyms: 4-Methoxy-M-toluic acid;4-METHOXY-3-METHYLBENZOIC ACID;ASISCHEM C71547;ASINEX-REAG BAS 12820340;RARECHEM AL BE 0539;4-METHXOY-3-METHYLBENZOIC ACID;4-METHOXY-3-METHYLBENZOIC ACID, 98+%;4-Methoxy-3-methylbenzoic acid3-Methyl-p-anisic acid
• CAS NO: 6880-04-2
• Molecular Formula: C₉H₁₀O₃
• Molecular Weight: 166.17
• EINECS: 1312995-182-4
• Product Categories: Acids and Derivatives;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;API intermediates;Acids & Esters;Anisoles, Alkyloxy Compounds & Phenylacetates
• Mol File: 6880-04-2.mol
• Article Data: 7

Chemical Properties

• Melting Point: 177-181 °C(lit.)
• Boiling Point: 285.3°C at 760 mmHg
• Flash Point: 114.2°C
• Appearance: /
• Density: 1.168g/cm³
• Vapor Pressure: 0.00132mmHg at 25°C
• Refractive Index: 1.54
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.54±0.10(Predicted)
• CAS DataBase Reference: 4-Methoxy-3-methylbenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methoxy-3-methylbenzoic acid(6880-04-2)
• EPA Substance Registry System: 4-Methoxy-3-methylbenzoic acid(6880-04-2)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 6880-04-2(Hazardous Substances Data)

Usage

Chemical Properties

Pale yellow or cream powder

InChI:InChI=1/C9H10O3/c1-6-5-7(9(10)11)3-4-8(6)12-2/h3-5H,1-2H3,(H,10,11)

Upstream product

• 14804-31-0 2-methyl-4-bromoanisole 
• 32723-67-4 3-methyl-4-anisaldehyde 
• 70347-04-5 4-Methoxy-3-methylbenzoesaeure-methylester 
• 53078-71-0 4-methoxy-3-methylbenzonitrile 
• 499-76-3 4-hydroxy-3-methylbenzoic acid 
• 77-78-1 dimethyl sulfate 
• 10024-90-5 4-methoxy-3-methylacetophenone 
• 108088-85-3 2-methyl-4-(trinitromethyl)anisole 
• 7664-41-7 ammonia 
• 7782-50-5 chlorine 
• 7288-04-2 2-methyl-4-propenyl-anisole 
• 64-19-7 acetic acid 
• 124-38-9 carbon dioxide 
• 578-58-5 2-methylmethoxybenzene 

Downstream Products

• 59931-48-5 4-methoxy-3-methylbenzoyl chloride 
• 2206-43-1 4-methoxyisophthalic acid 
• 82045-52-1 1-<2-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-5-methoxy-4-methylphenyl>ethanone 
• 62316-29-4 5-Chlor-4-methoxy-3-methylbenzoesaeure 
• 50741-92-9 2-methyl-4-nitroanisole 
• 808750-20-1 3-bromo-4-methoxy-5-methylbenzoic acid 
• 808750-30-3 (1'RS)-7-bromo-6-methoxy-8-[1'-methoxy-(3'-methoxy-7'-vinylphenyl)-methyl]-2,2,5-trimethyl-4H-benzo[1,3]dioxine 
• 808750-36-9 (7-bromo-6-methoxy-2,2,5-trimethyl-4H-benzo[1,3]dioxin-8-yl)-(3'-methoxy-7'-vinylphenyl)methanone 
• 808750-23-4 3-bromo-4-methoxy-5-methylphenol 
• 808750-22-3 3-bromo-4-methoxy-5-methyl benzaldehyde 
• 808750-21-2 (3-bromo-4-methoxy-5-methylphenyl)-methanol 
• 808750-24-5 3-bromo-2,6-bis(hydroxymethyl)-4-methoxy-5-methylphenol 
• 808750-35-8 2-[(7-bromo-6-methoxy-2,2,5-trimethyl-4H-benzo[1,3]dioxin-8-yl)-methoxy-methyl]-3-methoxy-benzaldehyde 
• 808750-29-0 (1'RS)-(7-bromo-6-methoxy-2,2,5-trimethyl-4H-benzo[1,3]dioxin-8-yl)-(3'-methoxy-7'-vinylphenyl)-methanol 

Relevant articles and documents

THERAPEUTIC COMPOUNDS

This invention relates to a novel class of substituted amino-ethoxy benzene derivatives of formula (I) which are inhibitors of serine proteases and to their use in treating aberrant serine protease activity in a mammal, contraception, anti-coagulant methods and methods for treating aberrant cell proliferation, tumours, cancer, angiogenesis, angiogenesis-based retinopathies, autoimmummune disease, inflammation, skin disease, arthritis, rheutmatoid arthritis, asthma, osteoarthritis and multiple sclerosis. (I), Wherein Rm, Rn, Rp, Rq, V, W, X, Y and R8 are as defined in the claims.

Carboxylation of anisole derivatives with CO and O2 catalyzed by Pd(OAc)2 and molybdovanadophosphates

Anisole and its homologues were carboxylated under the influence of CO and O2 catalyzed by Pd(OAc)2 combined with molybdovanadophosphates (HPMoV) under mild conditions to give the corresponding carboxylic acids in fair to good yields; for instance, anisole underwent the carboxylation under a mixed gas of CO (0.5 atm) and O2 (0.5 atm) in the presence of Pd(OAc)2 (5 mol%) and H5PMo 10V2O40·nH2O (2 mol%) to form an isomeric mixture of anisic acids in good yield.

1,2-disubstituted 1,4-dihydro-4-oxoquinoline compounds

The present invention relates to substituted 1,4-dihydro-4-oxoquinolines having antiviral activity. The substituents are present at positions 1, 2 and at least one of 5-8 positions of the quinoline ring.